Abstract
Earlier studies by our group indicated that methionine enkephalin enhanced PHA induced lymphocyte proliferation in mice, active rosette forming cells and NK cells in the cells of normal volunteer and cancer patients,(Plotnikoff et. al., 1985). More recently, several groups have reported that methionine enkephalin stimulates macrophage function as well as chemotaxis(Foris, 1984; Weber, 1984). Finally several groups have reported increased lymphokine production by methionine enkephalin(Brown, et al., 1985; Youkilis et al.,1985).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Brown, S. L. and Van Epps, E. E., 1985, Beta endorphin (BE), met-enkephalin (ME), and corticotrophin (ACTH) modulate the production of gamma interferon ( INF) in vitro, Fed. Proc., 44: 949.
Einhorn, S., Blomgren, H., Stander, H., and Troye, M., 1983, Activity following treatment with Interferon In Vivo, in: “Mediation of Cellular Immunity in Cancer by Immune Modifiers”, M. A. Chirigos, ed., Raven Press, New York.
DeMaeyer, G., Galasso, G., and Schellenkens, H., eds. 1983, in: “The biology of the interferon system”, 347–352, Elsevier/North Holland Biomedical Press, Amsterdam.
Foris, G., Medgyesi, G. A., Gyimesi, E., and Hauck, M., 1984, Met-enkephalin: induced alterations of macrophage functions, Mol. Immun., 21: 747.
Plotnikoff, N. P., Murgo, A. J., Miller, G. C., Corder, C. N., and Faith, R. E., 1985, Enkephalins: Immunomodulators, Fed. Proc. 44: 118.
Plotnikoff, N. P., Miller, G. C., Wybran, J., and Nimeh, N. F., April 10, 1985, Methionine enkephalin T-cell enhancement in Kaposis’ sarcoma, Serono Symposium, Copley Plaza Hotel, Boston, Recent Advances in Primary and Acquired Immunodeficiencies (in Press).
Weber, R. J., and Pert, C. B., 1984, Opiatergic modulation of the immune system, in: “Central and Peripheral Endorphins: Basic and Clinical Aspects”, E. E. Muller and A. R. Genezzani, eds., Raven Press, New York.
Youkilis, E., Chapman, J., Woods, E., and Plotnikoff, N., 1985, In Vivo immunostimulation and increased in vitro production of interleukin 1 (IL-1) activity by met-enkephalin, Int. J. Immunopharm., 7: 79.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 Springer Science+Business Media New York
About this chapter
Cite this chapter
Plotnikoff, N.P., Miller, G.C., Solomon, S., Faith, R.E., Edwards, L., Murgo, A.J. (1986). Methionine Enkephalin: T-Cell Enhancement in Normal Volunteers (in Vivo). In: Plotnikoff, N.P., Faith, R.E., Murgo, A.J., Good, R.A. (eds) Enkephalins and Endorphins. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0557-4_31
Download citation
DOI: https://doi.org/10.1007/978-1-4899-0557-4_31
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4899-0559-8
Online ISBN: 978-1-4899-0557-4
eBook Packages: Springer Book Archive