Neuroendocrine Control of the Onset of Puberty

  • Margaret E. Wierman
  • William F. CrowleyJr.


Sexual maturation has been variously defined by biologists in the past, but all definitions have included the orderly sequence of maturational events culminating in reproductive competence. Despite the relatively uniform agreement as to the essential components of this process, so critical to the propagation of the species, there is little understanding of its regulation and even less of its control. What is clear is that this development stage, termed puberty in the human, is composed of at least three distinct beiological processes: gonadal maturation, adrenal maturation, and a somatic growth spurt.


Sexual Maturation Adrenal Androgen Gonadal Dysgenesis GnRH Secretion Neuroendocrine Control 
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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Margaret E. Wierman
    • 1
  • William F. CrowleyJr.
    • 1
  1. 1.Reproductive Endocrine UnitMassachusetts General Hospital and Harvard Medical SchoolBostonUSA

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