New Conjugate Polymers — A Marriage Between Synthetic and Natural Polymers

  • Naoya Ogata

Abstract

Chemical modifications of enzymes such as Lipase or Tripsine to prepare novel enzyme conjugates were carried out by using telechelic oligo(N-isopropylacrylamide) which showed reversible dissolution-precipitation behaviors in water. The temperature-responsive enzyme conjugates retained the same enzymatic activities as native enzymes and recovery of the enzyme conjugates was possible by a simple temperature change to precipitate the enzyme conjugate out of the water solution and they were able to reuse in cycles without denaturation. This novel modulated systems is very useful for applications as a novel bioreactor system in comparison with immobilized enzyme systems.

Keywords

Acrylic Acid Native Enzyme Recycling System Enzyme Conjugate Butyl Methacrylate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Naoya Ogata
    • 1
  1. 1.Department of ChemistrySophia UniversityChiyoda-Ku, Tokyo 102Japan

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