Skip to main content
SpringerLink
Log in

Synthesis and Biological Activities of Endo-3,6-Epoxy-1,2,3,6-Tetrahydrophthalimide and Its Polymers

  • Chapter
Polymers and Other Advanced Materials

  • 893 Accesses

Abstract

The high molecular weight antitumor compounds(HMAC) are attracting much interest from the standpoints of polymers synthesis as well as drug development, because of their high specificity of action, low toxic side effects and longer duration of drug action as compared with low molecular weight antitumor compounds(LMAC).1–9 HMAC may be combined with large molecules in the living body and be slowly released into the biological fluids, giving effective concentrations over long periods.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. S. Ozaki, Y. Ike, H. Mizuno, K. Ishikawa and H. Mon, Bull.Chem.Soc.Japan, 50, 2406 (1977).

    Article  CAS  Google Scholar 

  2. P. P. Umrigar, S. Ohashi and G. B. Butler, J.Polym.Sci.,Polym.Chem.Ed., 17, 351 (1919).

    Article  Google Scholar 

  3. M. Akashi, K. Beppu, I. Kikuchi and N. Mizauchi, J. Mcromol. Sci-Chem. ED.,17, 351 (1986).

    Google Scholar 

  4. R. M. Ottenbrite, J. Mcrowol. Sci. chem., A22(57), 819(1985).

    Google Scholar 

  5. T. Oucin, H. Juzei, Y. Sakamoto, H. Chikachita and O. Vogl, J.Polym.Sci.,Polym.Chem. Vol.23, 2059(1986).

    Google Scholar 

  6. R. M. Ottenbrite, J. Sunamoto, T. Sato, K. Kojima, K. Sahara, K. Hara, M. Oka, J. Bioact & Compati. Polym. 3, 184,(1988).

    Article  CAS  Google Scholar 

  7. G. Butler, J. Macromol Sci-Chem., A13(3), 351 (1979).

    Article  Google Scholar 

  8. N. J. Lee, C. S. Ha, and W. J. Cho, J.Macromol.Sci-Chem., 29, 2, 161(1992).

    Article  Google Scholar 

  9. N. J. Lee, C. S. Ha, and W. J. Cho, Bioact.& Compati.Polym. 7, 39(1992).

    Article  Google Scholar 

  10. J. G. Jeong, N. J. Lee, C. S. Ha and W. J. Cho, Proc. 3rd Pacific Polymer Conf., Gold Coast, Australia, Dec.13–17,pp.75–76(1993).

    Google Scholar 

  11. D. Y. Lee, N. J. Lee, J. G. Jeong, C. S. Ha and W. J. Cho, The Society of Polymer Science, Japan, 797 Chapaffil l0/12–10/14.(1994).

    Google Scholar 

  12. G. T. Gam, J. G. Jeong, N. J. Lee, C. S. Ha and W. J. Cho, J.Appl.Polym.Sci. in print(1995).

    Google Scholar 

  13. G. T. Gam, J. G. Jeong, N. J. Lee, C. S. Ha and W. J. Cho, IUPAC International Symposium on Functional and High Performance Polymers, Taipei, Taiwan, Nov. 14–16,p.(1994).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Polymer Science and Engineering, Pusan National University, Pusan, 609-735, Korea

    Gi Cheol Kim, Jin Gon Jeong, Chang Sik Ha & Won Jei Cho

  2. Department of Premedical Sciences, Kosin University, Pusan, 602-735, Korea

    Neung Ju Lee

Authors
  1. Gi Cheol Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jin Gon Jeong
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Neung Ju Lee
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Chang Sik Ha
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Won Jei Cho
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. State University of New York at Buffalo, Buffalo, New York, USA

    Paras N. Prasad

  2. University of Cincinnati, Cincinnati, Ohio, USA

    James E. Mark

  3. Standard and Industrial Research Institute of Malaysia, Kuala Lumpur, Malaysia

    Ting Joo Fai

Rights and permissions

Reprints and permissions

Copyright information

© 1995 Springer Science+Business Media New York

About this chapter

Cite this chapter

Kim, G.C., Jeong, J.G., Lee, N.J., Ha, C.S., Cho, W.J. (1995). Synthesis and Biological Activities of Endo-3,6-Epoxy-1,2,3,6-Tetrahydrophthalimide and Its Polymers. In: Prasad, P.N., Mark, J.E., Fai, T.J. (eds) Polymers and Other Advanced Materials. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0502-4_28

Download citation

  • DOI: https://doi.org/10.1007/978-1-4899-0502-4_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0504-8

  • Online ISBN: 978-1-4899-0502-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation