Pharmacological Agents and the Release of Arachidonic Acid and Prostaglandin Biosynthesis by Rabbit Iris Muscle
Arachidonic acid (AA), the precursor of prostaglandins (PGs) and other biological active substances, is found mainly esterified to membrane phospholipids, almost exclusively in the 2-acyl position, from which it could be released by the action of lipases (Lands and Samuelson, 1968; Vogt, 1978) and reincorporated by a deacylation-reacylation cycle (for reviews see Hill and Lands, 1970; Holub and Kuksis, 1978; Irvine, 1982).
KeywordsArachidonic Acid Arachidonic Acid Release Myoinositol Phosphate Rabbit Iris Iris Muscle
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