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Pharmacological Agents and the Release of Arachidonic Acid and Prostaglandin Biosynthesis by Rabbit Iris Muscle

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Phospholipid Research and the Nervous System

Part of the book series: FIDIA Research Series ((FIDIA,volume 4))

Abstract

Arachidonic acid (AA), the precursor of prostaglandins (PGs) and other biological active substances, is found mainly esterified to membrane phospholipids, almost exclusively in the 2-acyl position, from which it could be released by the action of lipases (Lands and Samuelson, 1968; Vogt, 1978) and reincorporated by a deacylation-reacylation cycle (for reviews see Hill and Lands, 1970; Holub and Kuksis, 1978; Irvine, 1982).

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Abbreviations

PG:

prostaglandin

PAF:

platelets-activating factor

NE:

norepinephrine

DG:

1, 2-diacylglycerol

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© 1986 Springer-Verlag Berlin Heidelberg

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Abdel-Latif, A.A., Naderi, S., Yousufzai, S.Y.K. (1986). Pharmacological Agents and the Release of Arachidonic Acid and Prostaglandin Biosynthesis by Rabbit Iris Muscle. In: Horrocks, L.A., Freysz, L., Toffano, G. (eds) Phospholipid Research and the Nervous System. FIDIA Research Series, vol 4. Springer, New York, NY. https://doi.org/10.1007/978-1-4899-0490-4_9

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  • DOI: https://doi.org/10.1007/978-1-4899-0490-4_9

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4899-0492-8

  • Online ISBN: 978-1-4899-0490-4

  • eBook Packages: Springer Book Archive

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