Effects of Ethanol on Brain Phospholipids

  • Grace Y. Sun
  • Hsueh-Meei Huang
  • Albert Y. Sun
Part of the FIDIA Research Series book series (FIDIA, volume 4)


The primary mode of action of ethanol is on the neural membranes. While excessive intake can result in acute intoxication, development of tolerance and physical dependence is frequently associated with long term intake. On withdrawal of the drug, the behavioral manifestation of hyperexcitability is shown in man, as well as in animal models. In spite of the behavioral and physiological effects known to be associated with alcoholism, the molecular site of ethanol action in the central nervous system has not been clearly elucidated.


Chronic Ethanol Brain Membrane Acidic Phospholipid Synaptic Plasma Membrane Brain Phospholipid 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • Grace Y. Sun
    • 1
  • Hsueh-Meei Huang
    • 1
  • Albert Y. Sun
    • 1
  1. 1.Sinclair Comparative Medicine Research Farm and Biochemistry DepartmentUniversity of MissouriColumbiaUSA

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