Pediatric Oncologic Emergencies

  • Maria Santorineou


Pediatric oncologic emergencies can be defined as the clinical situations that arise from the disease process or from complications of its treatment or from both.


Uric Acid Serum Uric Acid Disseminate Intravascular Coagulation Superior Vena Cava Spinal Cord Compression 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Selected Readings


  1. Allegretta GJ, Weisman SJ, Altman Ai: Oncologic emergencies. I. Metabolic and space-occupyingGoogle Scholar
  2. consequences of cancer and cancer treatment. Pediatr Clin North Am 32:601, 1985. Allegretta GJ, Weisman SJ, Altman AJ: Oncologie emergencies. II. Hematologic and infectiousGoogle Scholar
  3. complications of cancer and cancer treatment. Pediatr Clin North Am 32:613, 1985. Lampkin BC, Gruppo RA, Lobel JS, et al: Pediatric hematologic and oncologic emergencies.Google Scholar
  4. Emerg Med Clin North Am 1:63, 1983.Google Scholar

Superior Vena Cava Syndrome

  1. Issa PY, Brihi ER, Janin Y, et al: Superior vena cava syndrome in childhood: Report of ten cases and review of the literature. Pediatrics 71: 337, 1983PubMedGoogle Scholar
  2. Perez CA, Presant CA, van Amburg AL III: Management of superior vena cava syndrome. Semin Oncol 5: 123, 1978.PubMedGoogle Scholar

Spinal Cord Compression

  1. Allen JC: Management of metastatic epidural disease. J Pediatr 104: 241, 1984PubMedCrossRefGoogle Scholar
  2. Hayes FA, Thompson EI, Hvizdala E: Chemotherapy in management of epidural tumor. J Pediatr 104: 221, 1984PubMedCrossRefGoogle Scholar
  3. Milhorat TH: Tumors of the spinal cord and peripheral nerves, in Pediatric Neurosurgery. Philadelphia, FA Davis, 1978.Google Scholar
  4. Pui CH, Dahl GV, Hustu HD, et al: Epidural spinal cord compression as the initial finding inGoogle Scholar
  5. childhood acute leukemia and non-Hodgkin lymphoma. J Pediatr 106: 788, 1985.CrossRefGoogle Scholar
  6. Weinblatt MF, and Kenigsberg K: Paraplegia in children with malignant teratoma. Cancer 56:2140,1985Google Scholar

Hyperleukocytosis Syndrome

  1. Ablin AR: Managing the problem of hyperleukocytosis in acute leukemia. Am J Pediatr Hematol Oncol 6: 287, 1984.PubMedCrossRefGoogle Scholar
  2. Cohen LF, Balow JE, Magrath IT, et al: Acute tumor lysis syndrome: A review of 37 patients with Burkitt’s lymphoma. Am J Med 68: 486, 1980.PubMedCrossRefGoogle Scholar
  3. Gilchrist GS, Fountain KS, Dearth JC, et al: Cranial irradiation in the management of extreme leukemic leukocytosis complicating childhood acute lymphocytic leukemia. J Pediatr 98: 257, 1981.PubMedCrossRefGoogle Scholar
  4. McKee LC, and Collins RC: Intravascular leukocyte thrombi and aggregates as a cause for morbidity and mortality in leukemia. Medicine (Baltimore) 53: 436, 1974.Google Scholar
  5. Milligan DW, and Tooke JE: Microvascular changes in hyperleukocytic leukaemia. Br J Haematol 58: 380, 1984.PubMedCrossRefGoogle Scholar

Acute Intraabdominal Emergencies

  1. Ramsay NKC, Dehner LP, Coccia PF, et al: Acute hemorrhage into Wilms’ tumor. J Pediatr 91: 763, 1977.PubMedCrossRefGoogle Scholar
  2. Rosenfeld M, Rodgers BM, Talbert JL: Wilms’ tumor with acute abdominal pain. Arch Surg 112: 1080, 1977.PubMedCrossRefGoogle Scholar

Metabolic Emergencies

  1. Brenner BM, Lazarus JM: Acute Renal Failure. Philadelphia, WB Saunders, 1983, pp 442-443. DeFronzo RA, Bia M, Smith D: Clinical disorders of hyperkalemia. Annu Rev Med 33:521, 1982. Edelman W (ed): Pediatric Kidney Disease. Boston, Little Brown, 1978.Google Scholar
  2. Jaffe N, Paed D, Kim BS, et al: Hypocalcemia—a complication of childhood leukemia. Cancer 29: 392, 1972.PubMedCrossRefGoogle Scholar
  3. Perkin RM, and Levin DL: Common fluid and electrolyte problems in the pediatric intensive care unit. Pediatr Clin North Am 27: 567, 1980.PubMedGoogle Scholar
  4. Segar WE, Chesney RW: Disorders of electrolyte metabolism. Pediatr Ann 10: 28, 1981.Google Scholar

Hematologic Emergencies

  1. Feusner J: The use of platelet transfusions. Am J Pediatr Hematol Oncol 6: 255, 1984.PubMedCrossRefGoogle Scholar
  2. Neiburg PJ, Stockman JA: Rapid correction of anemia with partial exchange transfusion. Am J Dis Child 131: 131, 1977.Google Scholar
  3. Strauss RG: The role of granulocytic transfusions. Am J Pediatr Hematol Oncol 6:247, 1984. Corrigan J: Disseminated intravascular coagulation: Pathogenesis, diagnosis and management, in,Google Scholar
  4. Lusher JM and Barnhart MI (eds): Acquired bleeding disorders in children: Abnormalities of Google Scholar
  5. hemostasis. New York, Mason Publishing, 1981, pp 27-39.Google Scholar

Infectious Emergencies

  1. Brown AE: Management in the febrile neutropenic patient with cancer: Therapeutic considerations. J Pediatr 106: 1035, 1985.PubMedCrossRefGoogle Scholar
  2. Eichenwald HF: Antimicrobial therapy in infants and children: Update 1976-1985. Part II. J Pediatr 107: 3377, 1985.Google Scholar
  3. Geelhoed GW, Hubbard SB, Powell RD, et al: Clinical characteristics of Pneumocystis carinii pneumonia. Am Surg 45: 293, 1979.PubMedGoogle Scholar
  4. Maddux MS, Bamere SL: A review of complications of amphotericin B therapy: Recommenda-tions for prevention and management. Drug Intell Clin Pharm, March 14, 1980, pp 177 - 181. Pizzo PA: Infectious complications in the child with cancer. I. Pathophysiology of the compro- mised host and management of the febrile cancer patient. J Pediatr 98:341, 1981.Google Scholar
  5. Pizzo PA: Infectious complications in the child with cancer. II. Management of specific infectious organisms. J Pediatr 98: 513, 1981.PubMedCrossRefGoogle Scholar
  6. Pizzo PA, Commers J, Cotton D, et al: Approaching the controversies in antibacterial management of cancer patients. Am J Med 76: 436, 1984.PubMedCrossRefGoogle Scholar
  7. Pizzo PA, Thaler M, Hathorn J, et al: New beta-lactam antibiotics in granulocytopenic patients: New options and new questions. Am J Med 79 (Suppl 2A): 75, 1985.PubMedCrossRefGoogle Scholar
  8. Prober CG, Kirk LE, Keevey RE: Acyclovir therapy of chickenpox in immunosuppressed children—A collaborative study. J Pediatr 101: 622, 1982.PubMedCrossRefGoogle Scholar


  1. Friedman AL, Segar WE: Antidiuretic hormone excess. J Pediatr 94: 521, 1979.PubMedCrossRefGoogle Scholar
  2. Priest JR, Ramsay NRC, Steinberz PG, et al: A syndrome of thrombosis and hemorrhage complicating L-asparaginase therapy for childhood acute lymphoblastic leukemia. J Pediatr 100: 984, 1982.PubMedCrossRefGoogle Scholar
  3. Kucuk O, Kwaan HC, Gunnar W, et al: Thromboembolic complications associated with L-asparaginase therapy. Cancer 55: 702, 1985.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • Maria Santorineou
    • 1
  1. 1.Department of PediatricsAlbert Einstein College of Medicine, Bronx Municipal Hospital CenterBronxUSA

Personalised recommendations