Typhlitis and Related Acute Gastrointestinal Problems

  • Peter H. Wiernik


Typhlitis is a necrotizing lesion of the cecum and adjacent colon that occurs in a setting of cancer chemotherapy and neutropenia. It is primarily a complication experienced by acute leukemia patients, but it has also been observed in patients with the more common solid tumors.1 Typhlitis often presents as an acute intraabdominal emergency. It may require surgical intervention, but in many instances it may be successfully managed medically. Typhlitis is a potentially grave complication, and irrespective of management, the outcome is often death. Early recognition of the problem, and guidelines for surgical intervention, may improve the outcome of patients with this complication.


Acute Leukemia Cytosine Arabinoside Acute Leukemia Patient Pneumatosis Cystoides Intestinalis Neutropenic Enterocolitis 
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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • Peter H. Wiernik
    • 1
    • 2
    • 3
  1. 1.Department of OncologyMontefiore Medical CenterBronxUSA
  2. 2.Division of Medical OncologyAlbert Einstein College of MedicineBronxUSA
  3. 3.Albert Einstein Cancer CenterBronxUSA

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