Meningeal Leukemia and Carcinomatosis

  • Joachim Z. Fuks
  • Stuart Marcus


The term “neoplastic meningitis” refers to diffuse or multifocal seeding of the leptomeninges by tumor cells. Pure neoplastic meningitis is defined by the presence of leptomeningeal involvement by tumor cells in the absence of concomitant malignant metastasis in the brain or spinal cord. Primary leptomeningeal tumors such as primary melanomatosis or primary glioblastomatosis are exceptionally rare (Table 1). Secondary neoplastic meningitis can be divided into two groups. The first includes meningeal leukemias and lymphomas, and the second includes leptomeningeal metastases of solid tumor, the so-called “meningeal carciomatosis.”


Chronic Lymphocytic Leukemia Cranial Nerve Palsy Leptomeningeal Metastasis Fuse Category Central Nervous System Metastasis 
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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • Joachim Z. Fuks
    • 1
  • Stuart Marcus
    • 2
  1. 1.Division of OncologyAlbert Einstein College of Medicine/Montefiore Medical CenterBronxUSA
  2. 2.Division of OncologyAlbert Einstein College of Medicine/Montefiore Medical CenterBronxUSA

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