Abstract
Several biologically active compounds are capable of forming intermolecular non-covalent complexes with deoxyribonucleic acid (DNA) under free energy changes of less than 40 kJ/mol (approximately 10 kcal/mol)[1–4]. These complexes are in the first place investigated on isolated DNA. There is, however, indication that they are also present in biological systems, where the nucleic acids exist in their natural state[5,6].
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Löber, G., Klarner, R. (1985). Water and DNA-Drug Interaction. In: Pullman, A., Vasilescu, V., Packer, L. (eds) Water and Ions in Biological Systems. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0424-9_74
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DOI: https://doi.org/10.1007/978-1-4899-0424-9_74
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