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An ESR Study of the Oxidation and Reduction of Bisulfite (Hydrated Sulfur Dioxide) in Biological Systems

  • Colin F. Chignell
  • Carolyn Mottley
  • Kandiah Sivarajah
  • Thomas E. Eling
  • Ronald P. Mason

Abstract

Sulfur dioxide is recognized as a major air pollutant, particularly near large cities (Rall, 1974), while the ionized forms, bisulfite and sulfite, are found as preservatives in food and wine. In the lung, sulfur dioxide is hydrated rapidly according to the following equation,
$$ {H_2}O + S{O_2} \rightleftharpoons HSO_3^ - + {H^ + }$$
with the equilibrium constant 1.07 × 102 mole/liter. The bisulfite anion is a weak acid which dissociates according to the reaction,
$$HSO_3^ - + {H_2}O \rightleftharpoons {H_3}{O^ + } + SO_3^{ - 2}$$
with an equilibrium constant of 1.07 × 107 mole/liter. At pH values above 7 the equilibrium lies to the right and sulfite predominates, although there is always an equilibrium between sulfite and bisulfite. In this paper the terminology (bi)sulfite will be used when it cannot be determined which species is involved in a given reaction.

Keywords

Electron Spin Resonance Sulfur Dioxide Methyl Viologen Sulfur Trioxide Microsomal Incubation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • Colin F. Chignell
    • 1
  • Carolyn Mottley
    • 1
  • Kandiah Sivarajah
    • 1
  • Thomas E. Eling
    • 1
  • Ronald P. Mason
    • 1
  1. 1.Laboratory of Environmental BiophysicsNational Institute of Environmental Health SciencesUSA

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