Potassium Loss and Water Uptake of Stimulated Frog Muscles

  • László Nagy
  • Péter Práger

Abstract

Ernst and Csucs (1929) were the first to demonstrate that when stimulating the muscle directly — i.e. when the stimulating current passes through the whole muscle — changes take place in the K+-Na+-Cl- and P- content. Mond and Netter (1930) as well as Achelis (1932) repv.td similar results. Hodgkin and Horovitz (1959) demonstrated Na +-K+ exchange in single muscle fibers stimulated directly. Tigyi (1956) investigated isolated frog sartorii in a Ringer solution containing K42 radioactive isotope. Besides potassium loss, the directly stimulated muscles showed a significant increase in specific activity. Later different authors obtained conflicting results. W decided, therefore, to reinvestigate the problem. Changes of the K+ and water content of frog muscle caused by the electric stimulating current were measured in order to obtain new data about the nature of these changes. We used blockers of ionic currents and of metabolism to find out their effect on the changes mentioned above.

Keywords

Water Uptake Relative Water Content Frog Muscle Electric Current Pulse Single Muscle Fiber 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Achelis, J. D., 1932, Über die Polarisationskapacität (“Permeabilität”) des Skeletmuskels bei indirekter Reizung, Pflügers Archiv für die gesamte Physiologie, 230: 412.CrossRefGoogle Scholar
  2. Ernst, E., and Csucs, L., 1929, Untersuchungen über Muskelkontraktion, IX. Mitt. Permeabilität und Tätigkeit, Arch.Ges.Physiol., 223: 663.Google Scholar
  3. Hodgkin, A. L., and Horowitz, P., 1959, Movements of Na and K in single muscle fibers, J.Physiol., 145: 505.Google Scholar
  4. Mond, R., and Netter, H., 1930, Andert sich Ionpermeanilität des Muskels während seiner Tätigkeit? Pflügers Arch.Ges.Physiol., 224: 702.CrossRefGoogle Scholar
  5. Tigyi, J., 1956, K-Na-P izotópcsere a müködö sartoriusban, Kisérletes Orvostudom£ny, 8: 105.Google Scholar

Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • László Nagy
    • 1
  • Péter Práger
    • 1
  1. 1.Biophysical InstituteMedical UniversityPécsHungary

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