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Mechanisms of Proton-Hydroxide Flux Across Membranes

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Water and Ions in Biological Systems

Abstract

In both model and biological membranes, measurements of proton-hydroxide flux produce permeability coefficients that are orders of magnitude greater than those obtained with other monovalent ions. As a working hypothesis, we suggest that this large variance can be explained by the flux of protons along hydrogenbonded strands of associated water or protein in the hydrophobic plane of the membrane.

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References

  1. Hauser, H., Oldani, D. and Phillips, M.C. Biochemistry 12: 4507 (1973).

    Article  PubMed  CAS  Google Scholar 

  2. Nozaki, Y. and Tanford, C. Proc. Natl. Acad. Sci. USA 78: 4324 (1981).

    Article  PubMed  CAS  Google Scholar 

  3. Papahadjopoulos, D., Nir, S. and Ohki, S. Biochim. Biophys. Acta 266: 561 (1972).

    Article  PubMed  CAS  Google Scholar 

  4. Nichols, J.W., Hill, M.W., Bangham, A.D. and Deamer, D.W. Biochim. Biophys. Acta 596: 393 (1980).

    Article  PubMed  CAS  Google Scholar 

  5. Rossignol, M., Thomas, P. and Grignon, C. Biochim. Biophys. Acta 684: 195 (1982).

    Article  PubMed  CAS  Google Scholar 

  6. Pohl, W.G. Z. Naturforsch 37c: 120 (1982).

    CAS  Google Scholar 

  7. Biegel, C.M. and Gould, J.M. Biochemistry 20: 3474 (1981).

    Article  PubMed  CAS  Google Scholar 

  8. Nichols, J.W. and Deamer, D.W. Proc. Natl. Acad. Sci. USA 77: 2038 (1980).

    Article  PubMed  CAS  Google Scholar 

  9. Deamer, D.W. and Nichols, J.W. Proc. Natl. Acad. Sci. USA 80:1983 (in press).

    Google Scholar 

  10. Elamrani, K. and Blume A. Biochim. Biophys. Acta (in press).

    Google Scholar 

  11. Gutknecht, J. and Walter, A. Biochim. Biophys. Acta 641: 183 (1981).

    Article  PubMed  CAS  Google Scholar 

  12. Hopfer, V., Lehninger, A.L. and Lennarz, W.J. J. Membrane Biol. 2: 41 (1970).

    Article  Google Scholar 

  13. Papahadjopoulos, D. and Ohki, S. In Surface Chemistry of Biological Systems. Plenum Press, 1970. pp. 155–173.

    Google Scholar 

  14. Cafiso, D. and Hubbel, W. Biophys. J. 33: 114a (1981).

    Google Scholar 

  15. Bangham, A.D., DeGier, J. and Greville, G.D. Chem. Phys. Lipids 1: 225 (1967).

    Article  CAS  Google Scholar 

  16. Griffith, 0.H., Dehlinger, P.J. and Van, S.P. J. Membrane Biol. 15: 159 (1974).

    Google Scholar 

  17. Cass, A. and Finkelstein, A. J. Gen. Physiol. 50: 1756 (1784).

    Google Scholar 

  18. Eigen, M. and DeMaeyer, L. Proc. R. Soc. London Ser A 247: 505 (1958).

    Article  CAS  Google Scholar 

  19. Kanehisa, I.M. and Tsong, T.Y. J. Am. Chem. Soc. 100: 424 (1978).

    Article  CAS  Google Scholar 

  20. Papahadjopoulos, D., Jacobson, K., Nir, S. and Isac, T. Biochim. Biophys. Acta 311: 330 (1973).

    Article  PubMed  CAS  Google Scholar 

  21. Peterson, D.C. Biochim. Biophys. Acta 600: 666 (1980).

    Article  Google Scholar 

  22. Katz, B. In Nerve, Muscle and Synapse. McGraw-Hill, p. 61. (1966).

    Google Scholar 

  23. Nagle, J.F. and Morowitz, H.J. Proc. Natl. Acad. Sci. USA 75: 298 (1978).

    Article  PubMed  CAS  Google Scholar 

  24. Edmonds, D. Biochem. Soc. Symp. 46:91 (1980). London: The Biochemical Society.

    Google Scholar 

  25. Gutknecht, J. and Walter A. Biochim. Biophys. Acta 645: 161 (1981).

    Article  CAS  Google Scholar 

  26. Mitchell, P. and Moyle, J. Biochem. J. 104: 588 (1967).

    PubMed  CAS  Google Scholar 

  27. Itzuzu, K.T. J. Physiol. (Lond) 221: 15 (1972).

    Google Scholar 

  28. Meissner, G. and Young, R.C. J. Biol. Chem. 255: 6814 (1980).

    PubMed  CAS  Google Scholar 

  29. Crandall, E.D., Klocke, R.A. and Forster, R.E. J. Gen. Physiol. 57: 664 (1971).

    Article  CAS  Google Scholar 

  30. Pitman, M.G., Anderson, W.P. and Schaefer, N. In Regulation of Cell Membrane Activities in Plants. Marre E. and Ciferri 0. eds. pp. 147–160. North Holland, Amsterdam (1977).

    Google Scholar 

  31. Scheiner, S. Ann. New York Acad. Sci. 367: 493 (1981).

    Article  CAS  Google Scholar 

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Deamer, D.W., Nichols, J.W. (1985). Mechanisms of Proton-Hydroxide Flux Across Membranes. In: Pullman, A., Vasilescu, V., Packer, L. (eds) Water and Ions in Biological Systems. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0424-9_45

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  • DOI: https://doi.org/10.1007/978-1-4899-0424-9_45

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0426-3

  • Online ISBN: 978-1-4899-0424-9

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