Theoretical Models for Calcium Channels in Nerve Cells

  • Platon Kostyuk
  • Sergei Mironov


One of the important problems in modern biophysics is determination of the structure and function of different ionic channels in various excitable tissues. During the past three decades it became well established that there are three main types of ionic channels which differ in their kinetic, selective and pharmacological properties. These are sodium, potassium and calcium channels. Among them calcium channels appear to play the most significant role in the functioning of nerve cells (see, e.g. Llinas, 1979; Kostyuk, 1981). The reason for this lies in the fact that these channels are responsible not only for the electrical behaviour of nerve cells, but also provide a pathway for calcium ions into the cell. Entering the nerve cell Ca ions can trigger many different biochemical reactions related to the functioning, differentiation and proliferation of nerve cells (Minas, 1979; Kostyuk, 1981).


Calcium Channel Carboxylic Group Nerve Cell Energy Profile Extracellular Solution 
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Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • Platon Kostyuk
    • 1
  • Sergei Mironov
    • 1
  1. 1.A. A. Bogomoletz Institute of PhysiologyUkrainian Academy of SciencesKievUSSR

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