Hydration of DNA and Possible Role of Water in the Transition between Right- and Left-Handed Double Helix

  • G. M. Mrevlishvili
  • G. Sh. Japaridze
  • V. M. Sokhadze
  • Z. I. Chanchalashvili
  • D. A. Tatishvili


As we already know from the classical X-ray studies, the conformation of DNA double helix depends to a great extent on water and different cation content[1,2]. Unfortunately, until now we have been forced to consider structural parameters of DNA molecules only in terms of spatial molecular models[3]. Only recently a noticeable progress has been made in this field[4–10]. The obtained data show[5] that structural and dynamic properties of polynucleotide chains with definite nucleotide sequence lead to the forms of double helix radically differing from B-DNA conformation. We are considering so-called Z-DNA, or left handed DNA with the structure determined on the basis of X-ray analysis of monocrystals of oligonucleotides with alternating pur-pyr sequences[4–7].


Double Helix Excess Heat Capacity Eutectic Melting Mixture Melting Polynucleotide Chain 
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Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • G. M. Mrevlishvili
    • 1
  • G. Sh. Japaridze
    • 1
  • V. M. Sokhadze
    • 1
  • Z. I. Chanchalashvili
    • 1
  • D. A. Tatishvili
    • 1
  1. 1.Institute of PhysicsAcademy of Sciences of the Georgian USSRTbilisiUSSR

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