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Divalent Metals and Cancer

  • E. L. Andronikashvili

Abstract

The carcinogenic action of some metals was known long ago. However, their specific role remained obscure. The enormous role of metals in cancer development as all levels of biological functioning has been revealed during the last ten years. The beginning of these investigations should be dated back to 1969[1,2] when our papers devoted to the additional incorporation of metal ions in nucleic acids of transformed cells as compared to the norm were published.

Keywords

Circular Dichroism Spectrum Divalent Metal Doklady Akademii Nauk SSSR Polynucleotide Chain Mammary Gland Cancer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    E. L.Andronikashvili, Preprint of the Institute of Physics, Acad.Sci.of Georgian SSR, (1969).Google Scholar
  2. 2.
    E. L. Andronikashvili, L. M. Mosulishvili, A. I. Belokobylski, V. P. Manjgaladze, N. E. Kharabadze, E. Yu. Efremova, Doklady Akademii Nauk SSSR, 195,4, 979–982 (1970).Google Scholar
  3. 3.
    C. P. Flessel, A. Furst, S. B. Radding, Comparison of carcinogenic metals, in: “Metal Ions in Biological Systems,” Marcel Dekker Inc., N. Y. and Basel, v.10, pp. 24–54 (1980).Google Scholar
  4. 4.
    E. L. Andronikashvili and L. M. Mosulishvili, Human leukemia and trace elements, in: “Metal Ions in Biological Systems,” Marcel Dekker Inc., N. Y. and Basel, v.10, pp. 167–206 (1980).Google Scholar
  5. 5.
    M. Hrgovcic, C. F. Tessmer, F. B. Thomas, P. S. Ong, J. F. Gamble, and Shullenberger, Cancer, 32: 1512 (1979).CrossRefGoogle Scholar
  6. 6.
    E. L. Andronikashvili, L. M. Mosulishvili et al., J.Radioanal. Chem., 58: 1 49–59 (1980).CrossRefGoogle Scholar
  7. 7.
    L. V. Popova and S. V. Mazukha, Proc. of Voronezh Medical Institute, 94: 58 (1975).Google Scholar
  8. 8.
    L. K. Tkeshelashvili, I. S. Mepisashvili, L. M. Mosulishvili, and N. E. Kuchava, in: “Radiation Investigations,”Tbilisi, “Metsniereba,” 11:25–31 (1975);Google Scholar
  9. L. K. Tkeshelashvili, I. S. Mepisashvili, L. M. Mosulishvili, N. E. Kuchava, and J. N. Novikova, in: “Radiation Investigations,” Tbilisi, “Metsniereba,” 11:33–50 (1975).Google Scholar
  10. 9.
    E. L. Andronikashvili, L. M. Mosulishvili, L. K. Tkeshelashvili, A. N. Rcheulishvili, and A. E. Matevosyan, Bull.Experim. Biologii i Meditsiny, 82: 11 (1976).Google Scholar
  11. 10.
    W. E. Walker and B. L. Vallee, J.Biol.Chemistry, 234: 3257 (1959).Google Scholar
  12. 11.
    M. A. Sirover and L. A. Loeb, Science, 194: 1434 (1976).PubMedCrossRefGoogle Scholar
  13. 12.
    S. K. Zavriev, L. E. Minchenkova, M. Vorlickova, A. M. Kolchinsky, M. V. Volkenstein, and V. I. Ivanov. BBA, 564: 212 (1979).PubMedCrossRefGoogle Scholar
  14. 13.
    J. R. Monaselidze, Z. I. Chanchalashvili, G. N. Mgeladze, G. V. Majagaladze, and D. K. Tsitsishvili, Proc.VII All-Union Conf.on Calorimetry, Chernogolovka, 415 (1977).Google Scholar
  15. 14.
    Z. I. Chanchalashvili, G. V. Majagaladze, G. N. Mgeladze, and J. R. Monaselidze, Conformational Changes of Biopolymers in Solutions, Proc.III All-Union Conf., Tbilisi, “Metsniereba,” p. 86 (1975).Google Scholar

Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • E. L. Andronikashvili
    • 1
  1. 1.Institute of PhysicsAcademy of Sciences of the Georgian SSRTbilisiUSSR

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