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Effect of Taurine on Chloride Conductance and Excitability of Rat Skeletal Muscle Fibers

  • Diana Conte-Camerino
  • Flavia Franconi
  • Mercede Mambrini
  • Delia Mitolo-Chieppa
  • Federico Bennardini
  • Paola Failli
  • Shirley H. Bryant
  • Alberto Giotti
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 217)

Abstract

Taurine is found in mammalian skeletal muscle fibers and all other excitable tissues (17), but its function is not well understood (16). Abnormal taurine contents whether pathologically or experimentally induced are often associated with changes of excitability in heart (9), nerve (8,21), and retina (4). The taurine content is increased in skeletal muscle from the dystrophic chicken (23).

Keywords

Extensor Digitorum Longus Membrane Resistance Chloride Conductance Component Conductance Taurine Content 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Adrian, R.H., Chandler, W.K., and Hodgkin, A.L., 1970, Slow changes In potassium permeability in skeletal muscle, J. Physiol. (London), 208:645–668.Google Scholar
  2. 2.
    Adrian, R.H., 1982, Voltage-dependent behavior in excitable membranes, in: “Abnormal Nerve and Muscle as Impulse Generators”, J.W. Culp and J. Ochoa, eds., Oxford Press, New York, pp. 54–61.Google Scholar
  3. 3.
    Adrian, R.H., Action currents in transverse tubules, 1982, in: Abnormal Nerve and Muscle as Impulse Generators”, J.W. Culp and J. Ochoa, eds., Oxford Press, New York, pp. 595–701.Google Scholar
  4. 4.
    Berson, E.L., Hayes, K.C., Rabin, A.R., Schmidt, S.Y., and Watson, G., 1976, Retinal degeneration in cats fed casein: II Supplementation with methionine, cystelne or taurine, Invest. Ophthalmol., 15:52–58.PubMedGoogle Scholar
  5. 5.
    Bryant, S.H., 1969, Cable properties of external intercostal muscle fibers from myotonic and nonmyotonic goats, J. Physiol. (Lond), 204:539–550.Google Scholar
  6. 6.
    Bryant, S.H., Conte-Camerino, D., Franconi, F., Giotti, A., and Mambrini, M, 1985, Lack of antagonism by taurine on chloride channel block by anthracene-9-carboxylic acid in rat skeletal muscle, Brit. J. Pharmacol., 86:586P.Google Scholar
  7. 7.
    Conte-Camerino, D., Bryant, S.H., and Mitolo-Chieppa, D., 1982, Electrical properties of rat extensor digitorum longus muscle after chronic application of emetine to the motor nerve, Exp. Neurol., 77:1–11.PubMedCrossRefGoogle Scholar
  8. 8.
    Davison, A.N., and Kaczmarek, L.K., 1971, Taurine. A possible neurotransmitter?, Nature, 234:107–108.PubMedCrossRefGoogle Scholar
  9. 9.
    Dolara, P., Ledda, F., Mugelli, A., Mantelli, L., Zilletti, L., Franconi, F., and Giotti, A., 1978, Effect of taurine on calcium inotropism and electrical activity of the heart, in: “Taurine and Neurological Disorders”, A. Barbeau and R.J. Huxtable, eds., Raven Press, New York, pp. 151–159.Google Scholar
  10. 10.
    Dulhunty, A.F., 1978, The dependence of membrane potential on extracellular chloride concentration in mammalian skeletal muscle fibers, J. Physiol. (Lond), 276:67–82.Google Scholar
  11. 11.
    Durelli, L., Mutani, R., and Fassio, F., 1983, The treatment of myotonia: evaluation of chronic oral taurine therapy. Neurol., 33:559–603.Google Scholar
  12. 12.
    Entrikin, R.K., and Bryant, S.H., 1979, Suppression of myotonia in dystrophic chicken muscle by phenytoin, Am. J. Physiol., 237:C131–C136.PubMedGoogle Scholar
  13. 13.
    Franconi, F., Martini, F., Bennardini, F., Mangiapane, A., and Giotti, A., 1981, Taurine uptake in sarcolemma vesicles isolated from hypertrophic guinea pig hearts, Biochem. Pharmacol., 30:693–695.PubMedCrossRefGoogle Scholar
  14. 14.
    Green, J.R., and Margerison, D., 1978, Statistical Treatment of Experimental Data, Elseiver, New York, pp. 86–88.Google Scholar
  15. 15.
    Gruener, R., Bryant, H.J., Markovitz, D., Huxtable, R., and Bressler, R., 1976, Ionic actions of taurine on nerve and muscle membranes: electrophysiologic studies, in: “Taurine and Neurological Disorders”, A. Barbeau and R.J. Huxtable, eds., Raven Press, New York, pp. 225–246.Google Scholar
  16. 16.
    Huxtable, R.J., 1980, Does taurine have a function?, Fed Proc, 39:2678–2679.PubMedGoogle Scholar
  17. 17.
    Jacobson, J.G., and Smith, L.L.H., 1968, Biochemistry and physiology of taurine and taurine derivatives, Physiol. Rev., 48:424–511.Google Scholar
  18. 18.
    Krnjevic, K., 1974, Vertebrate synaptic transmission, Physiol. Rev., 54:418–540.Google Scholar
  19. 19.
    Krnjevic, K., and Puil, E., 1976, Electrophysiological studies on actions of taurine, in: “Taurine”, R.J. Huxtable, and A. Barbeau, eds., Raven Press, New York, pp. 179–189.Google Scholar
  20. 20.
    Krusz, J., Kendrick, Z.V., and Baskin, S.I., 1978, Taurine content in the pineal of the aging monkey, in: Aging in the Nonhuman Primate, Raven Press, New York, pp. 106–111.Google Scholar
  21. 21.
    Okamoto, K., Kimura, H., and Sakai, Y., 1983, Ionic mechanisms of the action of taurine on cerebellar Purkinje cell dendrites in vitro: intradendritic study, Brain Res., 260:261–269.PubMedCrossRefGoogle Scholar
  22. 22.
    Nistri, A., and Costanti, A., 1976, The action of taurine on the lobster muscle fiber and the frog spinal cord. Neuropharmacol., 15:635–641.CrossRefGoogle Scholar
  23. 23.
    Wilson, B.W., Peterson, D.W., and Lilyblade, A.L., 1965, Free amino acids of developing skeletal musculature of normal and genetically dystrophic chickens, Proc. Soc. Biol. Med., 119:104–108.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • Diana Conte-Camerino
    • 1
  • Flavia Franconi
    • 3
  • Mercede Mambrini
    • 1
  • Delia Mitolo-Chieppa
    • 2
  • Federico Bennardini
    • 4
  • Paola Failli
    • 4
  • Shirley H. Bryant
    • 5
  • Alberto Giotti
    • 4
  1. 1.Cattedra di Farmacologia e Farmacognosia, Facoltà di FarmaciaUniversita di BariItaly
  2. 2.Istituto di Farmacologia, Facoltà di MedicinaUniversità di BariItaly
  3. 3.Cattedra di Saggi e Dosaggi Farmacologici, Facoltà di FarmaciaUniversità di SassariItaly
  4. 4.Dipartimento di Farmacologia Preclinica e Clinica “M. Aiazzi Mancini”Università di FirenzeItaly
  5. 5.Department of Pharmacology and Cell Biophysics, College of MedicineUniversity of CincinnatiCincinnatiUSA

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