Effect of Taurine on Chloride Conductance and Excitability of Rat Skeletal Muscle Fibers

  • Diana Conte-Camerino
  • Flavia Franconi
  • Mercede Mambrini
  • Delia Mitolo-Chieppa
  • Federico Bennardini
  • Paola Failli
  • Shirley H. Bryant
  • Alberto Giotti
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 217)


Taurine is found in mammalian skeletal muscle fibers and all other excitable tissues (17), but its function is not well understood (16). Abnormal taurine contents whether pathologically or experimentally induced are often associated with changes of excitability in heart (9), nerve (8,21), and retina (4). The taurine content is increased in skeletal muscle from the dystrophic chicken (23).


Extensor Digitorum Longus Membrane Resistance Chloride Conductance Component Conductance Taurine Content 
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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • Diana Conte-Camerino
    • 1
  • Flavia Franconi
    • 3
  • Mercede Mambrini
    • 1
  • Delia Mitolo-Chieppa
    • 2
  • Federico Bennardini
    • 4
  • Paola Failli
    • 4
  • Shirley H. Bryant
    • 5
  • Alberto Giotti
    • 4
  1. 1.Cattedra di Farmacologia e Farmacognosia, Facoltà di FarmaciaUniversita di BariItaly
  2. 2.Istituto di Farmacologia, Facoltà di MedicinaUniversità di BariItaly
  3. 3.Cattedra di Saggi e Dosaggi Farmacologici, Facoltà di FarmaciaUniversità di SassariItaly
  4. 4.Dipartimento di Farmacologia Preclinica e Clinica “M. Aiazzi Mancini”Università di FirenzeItaly
  5. 5.Department of Pharmacology and Cell Biophysics, College of MedicineUniversity of CincinnatiCincinnatiUSA

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