Neural Regulation of Taurine Transport in Skeletal Muscle
Taurine is present at high concentration in skeletal muscles, and affects various electrophysiological and biochemical parameters of skeletal muscle; it hyperpolarized muscle fibers and decreased the duration of the action potential (3), and it enhanced the capacity for calcium uptake by sarcoplasmic reticulum (5). Response of isolated skeletal muscles to cholinergic stimulation is attenuated by taurine (9). With respect to the possible involvement of taurine in skeletal muscle pathology, it has been known that the skeletal muscle of dystrophic animals had a significantly higher amount of taurine (18). Experiments with myotonic muscles have shown that taurine prevents or reduces the electrical signs of muscular hyperexcitability and favors potassium accumulation into the muscle fibers (2,11).
KeywordsSoleus Muscle Extensor Digitorum Longus Myotonic Dystrophy Extensor Digitorum Longus Muscle High Frequency Stimulation
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