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Abnormal Visual Acuity and Retinal Morphology in Rhesus Monkeys Fed a Taurine-Free Diet During the First Three Postnatal Months

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 217))

Abstract

Over ten years ago, taurine was identified as an essential nutrient for cats (7). Without a dietary source of this amino acid, such as their natural taurine-rich diet of meat and fish, both kittens and adult cats undergo a decline in plasma and tissue taurine levels, reduced electroretinogram amplitudes with prolonged peak latencies, and progressive retinal degeneration which eventually results in blindness (8,24,26). As Dr. Sturman describes elsewhere in this volume, taurine deprivation of pregnant cats and their kittens also produces more widespread nervous system disturbances, including abnormal development of the cerebellum and visual cortex (19,27). Although cats appear to be unique in the severity of the effects produced by dietary taurine deprivation, it is now clear that they are not the only species affected. Recent studies of both human children and infant monkeys show that changes in retinal structure and function are associated with taurine deprivation.

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© 1987 Springer Science+Business Media New York

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Neuringer, M., Imaki, H., Sturman, J.A., Moretz, R., Wisniewski, H.M. (1987). Abnormal Visual Acuity and Retinal Morphology in Rhesus Monkeys Fed a Taurine-Free Diet During the First Three Postnatal Months. In: Huxtable, R.J., Franconi, F., Giotti, A. (eds) The Biology of Taurine. Advances in Experimental Medicine and Biology, vol 217. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0405-8_12

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  • DOI: https://doi.org/10.1007/978-1-4899-0405-8_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0407-2

  • Online ISBN: 978-1-4899-0405-8

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