The Solution Structures of Transfer RNA and Ribonuclease in Different Solvents
Small-angle neutron scattering studies from solution, especially those using contrast variation, have usually been done with the assumption that a macromolecule of well-defined structure exists in a homogeneous solvent. This might be a good approximation in certain cases, but it is not a correct assumption because the very presence of the macromolecule perturbs the solvent in an unknown way.
KeywordsInfinite Dilution Contrast Variation Excess Mass Partial Specific Volume Water Shell
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