Hepatitis B pp 45-53 | Cite as

Medical Consequences of the Carrier State

  • W. Thomas London


Chronic infection with hepatitis B virus (HBV) may lead to the development of chronic hepatitis (both chronic persistent and chronic active), post-necrotic cirrhosis and primary hepatocellular carcinoma (PHC). This statement, which does not sound particularly revolutionary now, is directly contrary to the consensus of experts circa 1960 (1). At that time, it was thought that neither infectious nor serum hepatitis (the terms used then) led to chronic liver disease. Chronic hepatitis and cirrhosis, it was thought, were caused by autoimmune or toxic reactions to unidentified agents.


Chronic Hepatitis Chronic Liver Disease Chronic Active Hepatitis Primary Hepatocellular Carcinoma Chronic Carrier 
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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • W. Thomas London
    • 1
  1. 1.Institute for Cancer ResearchFox Chase Cancer CenterPhiladelphiaUSA

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