Abstract
Hexachlorophene, the other major product derived from trichlorophenol (see Chapter 1), is a general poison effective in the control of bacteria classified as gram-positive. In the cosmetics industry, hexachlorophene is used as a preservative. For medical purposes hexachlorophene is used in the control of staphylococcal organisms. The bacteriacide has four main uses: treatment of acne and impetigo, cleansing of intact skin around burns and wounds, presurgical washing and cleansing of newborn infants, particularly the umbilical cord.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Lowbury, E. J. L., Lilly, H. A., and Bull, J. P. Disinfection of hands: Removal of transient organisms, British Medical Journal II, 230-232 (1964).
Martindale, The Extra Pharmacopoeia, 7th ed., The Pharmaceutical Press, London (1977), Chlorhexidene, p. 508.
Martindale, The Extra Pharmacopoeia, 7th ed., The Pharmaceutical Press, London (1977), Hexachlorophene, p. 522.
Kimbrough, R. D. Review of the toxicity of hexachlorophene, Archives of Environmental Health 23, 119(1971).
Kimbrough, R. D., and Gaines, R. D. Hexachlorophene effects on the rat brain. Study of high doses by light and electron microscopy, Archives of Environmental Health 23, 114–118 (1971).
Food and Drug Administration: Drug Bulletin, Health Service and Mental Health Administration, U.S. Department of Health, Education and Welfare, (December 1971).
Smyth, Robin. The Observer, 1 October 1979.
Givaudan statement, Morhange Talcum Power—France, July 1978.
Anonymous. The Guardian, 12 February 1980.
Hay, Alastair. Seveso: The Aftermath, Nature (London) 263, 538–540 (1976).
Gezon, H. M., Thompson, D. J., Rogers, K. D., Hatch, T. F., Rycheck, R. R., and Yee, R. Control of staphylococcal infections and disease in the newborn through the use of hexachlorophene bathing, Pediatrics 51, 2(II), 331–344 (1973).
Pleuckhahn, V. D. Hexachlorophene and the control of staphylococcal sepsis in a maternity unit in Geelong, Australia, Pediatrics 51, 2(II), 368–382 (1973).
Gezon, H. M., Schaberg, M. J., and Klein, J. O. Concurrent epidemics of staphylococcus aurens and Group A steptococcus disease in a newborn nursery—control with penicillin G and hexachlorophene bathing, Pediatrics 51, 2(II), 382–394 (1973).
Corner, B. D., Alder, G., Burman, D., and Gillespie, W. A. Hexachlorophene—Yes or No?, British Medical Journal 1, 636 (1977).
Editorial. Hexachlorophene—Yes or No?, British Medical Journal 1, 337 (1977).
Gluck, L. A perspective on hexachlorophene, Pediatrics 51(II), 400–412 (1973).
Hailing, H. Suspected link between exposure to hexachlorophene and malformed infants, Annals of the New York Academy of Sciences 320, 426–435 (1979).
Hailing, H. Misstänkt samband mellan hexaklorofenexposition och missbild ningsbörd, Swedish Medical Journal 74, 542–546 (1977).
Westerholm, B. Kommentar, Swedish Medical Journal 74, 545 (1977).
Larssen, Sune. Personal communication, 3 September 1980.
Maloney, M. H. Chlorhexidene a hexachlorophene substitute in the nursery, Nursing Times, 11 September 1975.
Tuke, W. Hibiscrub in the control of staphylococcal infection in neonates, Nursing Times, 11 September 1975.
Geoge, R. H. The effect of antimicrobial agents in the umbilical cord, Chemotherapy 3, 415–420 (1976).
Senior, N. Some observations on the formulation and properties of chlorhexidene, presented at Symposium on Skin-Environmental Responses and Protection organized by the Society of Cosmetic Chemists of Great Britain, Oxford, United Kingdom, 11 April 1972.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1982 Springer Science+Business Media New York
About this chapter
Cite this chapter
Hay, A. (1982). Hexachlorophene. In: The Chemical Scythe. Disaster Research in Practice. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0339-6_4
Download citation
DOI: https://doi.org/10.1007/978-1-4899-0339-6_4
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4899-0341-9
Online ISBN: 978-1-4899-0339-6
eBook Packages: Springer Book Archive