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Immunopathogenesis of Entamoeba histolytica

  • Sergio Arias-Negrete
  • Kris Chadee
Part of the Infectious Agents and Pathogenesis book series (IAPA)

Abstract

Entamoeba histolytica is an enteric protozoan parasite that infects up to 10% of the world’s population resulting in 100,000 deaths per year from amebic colitis and liver abscess.(1) The parasite’s distribution is worldwide. Humans are infected by two morphologically identical species of amoebae: Entamoeba histolytica Schaudinn, 1903, which is pathogenic and is capable of causing invasive amebiasis (but remains as a harmless commensal in the majority of infections), and Entamoeba dispar Brumpt, 1925, which is not pathogenic. Biochemical, immunological, genetic, and clinical characteristics support the existence of the two different and well-defined species.(2) This important finding has clarified the long-standing issue of interconverting amoebae and has explained the low percentage of individuals with clinical symptoms.

Keywords

Entamoeba Histolytica Amebic Liver Abscess Intestinal Amebiasis Histolytica Infection Histolytica Trophozoite 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Sergio Arias-Negrete
    • 1
  • Kris Chadee
    • 1
  1. 1.Institute of ParasitologyMcGill UniversitySte-Anne de BellevueCanada

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