Applications of DNA Fingerprints for the Study of Genetic Structure of Human Populations

  • J. McComb
  • M. H. Crawford
  • W. R. Leonard
  • M. S. Schanfield
  • L. Osipova
Part of the Stadler Genetics Symposia Series book series (SGSS)


The highly polymorphic nature of Variable Number Tandem Repeat (VNTR) loci have made these DNA markers useful in the examination of the genetic structure of human populations (Hartmann et al., 1994; McComb et al., 1995a). A VNTR locus is characterized by a sequence of DNA bases which is repeated over a section of DNA. The number of repeats is variable, sometimes few in number, and thus exhibiting a small allele. In other cases, the repeats are numerous, and the locus has a large allele. Thus, a VNTR allele can be characterized by its length.


Gene Flow Gene Pool Discriminant Function Fragment Size Variable Number Tandem Repeat 
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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • J. McComb
    • 1
  • M. H. Crawford
    • 1
  • W. R. Leonard
    • 2
  • M. S. Schanfield
    • 3
  • L. Osipova
    • 4
  1. 1.Laboratory of Biological AnthropologyUniversity of KansasLawrenceUSA
  2. 2.School of Human BiologyGuelph UniversityGuelphCanada
  3. 3.Analytical Genetic Testing CenterDenverUSA
  4. 4.Population Genetics Laboratory, Institute of Cytology and GeneticsRussian Academy of SciencesNovosibirskRussia

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