Genome Analysis in Farm Animals

  • James E. Womack
Part of the Stadler Genetics Symposia Series book series (SGSS)

Abstract

Genome research provides one of the exciting new frontiers in the life sciences. It should not be surprising that the agricultural sciences, long concerned with genetic improvement, are beginning to invest in building maps and localizing important traits to chromosomal regions. The following is a brief overview of the progress and problems of genome analysis in farm animals.

Keywords

Quantitative Trait Locus Bovine Leukemia Virus Leukocyte Adhesion Deficiency Cystic Fibrosis Gene Meiotic Product 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Andersson, L, Haley, C.S., Ellegren, H., Knott, S.A., Johansson, M., Andersson, K., Andersson-Eklund, L., Edfors-Lilja, I., Fredholm, M., Hansson, I., Hâkansson, J., and Lundström, K., 1994, Genetic mapping of quantitative trait loci for growth and fatness in pigs, Science 236: 1771.CrossRefGoogle Scholar
  2. Barendse, W. Armitage, S.M., Ryan, A.M., Moore, S.S., Clayton, D., Georges, M., and Womack, J.E., 1993, A genetic map of DNA loci in bovine chromosome 1, Genomics 18: 602.PubMedCrossRefGoogle Scholar
  3. Barendse, W., Armitage, S.M., Kossarek, LM., Shalom, A., Kirkpatrick, B.W., Ryan, A.M., Clayton, D., Li, L., Neibergs, H.L, Zhang, N., Grosse, W.M., Weiss, J., Creighton, P., McCarthy, F., Ron, M., Teale, A.J., Fries, R., McGraw, R.A., Moore, S.S., Georges, M., Soller, M., Womack, J.E., and Hetzel, D.J.S., 1994, A genetic linkage map of the bovine genome, Nature Genetics 6: 227.PubMedCrossRefGoogle Scholar
  4. Bishop, M.D., Kappes, S.M., Keele, J.W., Stone, R.T., Sunden, S.LF., Hawkins, G.A., Solinas Toldo, S., Fries, R., Grosz, M.D., Yoo, J., and Beattie, C.W., 1994, A genetic linkage map of cattle, Genetics 136: 619.PubMedGoogle Scholar
  5. Burt, D.W., Bumstead, N., Bitgood, J.J., Ponce de Leon, F.A., and Crittenden, LB., 1995, Chicken genome mapping: a new era in avian genetics, Trends in Genetics, 11:161–201.CrossRefGoogle Scholar
  6. Cowan, C.M., Dentine, M.R. Ax, R.L, and Schuler, LA., 1990, Structural variation around prolactin gene linked to quantitative traits in an elite Holstein sire family, Theor. Appl. Genet. 79: 577.Google Scholar
  7. Cockett, N.E., Jackson, S.P., Shay, T.L, Neilson, D., Moore, S.S. Steele, M.R., Barendse, W., Green, R.D., and Georges, M., 1994, Chromosomal location of the callipyge gene in sheep (Ovis aries) using bovine DNA markers, Proc. Natl. Acad. Sci. USA 91: 3019.PubMedCrossRefGoogle Scholar
  8. Echard, G., Broad, T.E., Hill, D., and Pearce, P, 1994, Present status of the ovine gene map (Ovis aries); comparison with the bovine map (Bos taurus), Mammal. Genome, 5: 324.CrossRefGoogle Scholar
  9. Ellegren, H., Chowdhary, B.P., Johansson, M., Marklund, L, Fredholm, M., Gustaysson, I., and Andersson, L., 1994, A primary linkage map of the porcine genome reveals a low rate of genetic recombination, Genetics 137: 1089.PubMedGoogle Scholar
  10. Fries, R. Eggen, A., and Stranzinger, G., 1990, The bovine genome contains polymorphic microsatellites, Genomics 8: 403.PubMedCrossRefGoogle Scholar
  11. Fries, R., Eggen, A., and Womack, J.E., 1993, The bovine genome map, Mammal. Genome 4: 405.CrossRefGoogle Scholar
  12. Gallagher, D.S., Threadgill, D.W., Ryan, A.M., Womack, J.E., and Irwin, D.M., 1993, Physical mapping of the lysozyme gene family in cattle, Mammal. Genome 4: 368.CrossRefGoogle Scholar
  13. Georges, M., Drinkwater, R., King, T., Mishra, A., Moore, S.S., Nielsen, D., Sargeant, LS., Sorensen, A., Steele, M.R., Zhao, X., Womack, J.E., and Hetzel, J., 1993a, Microsatellite mapping of a gene affecting horn development in Bos taurus, Nature Genetics 4: 206.PubMedCrossRefGoogle Scholar
  14. Georges, M., Dietz, A.B., Mishra, A., Nielsen, D., Sargeant, L, Sorensen, A., Steele, M.R., Zhao, X., Leipold, H., and Womack, J.E., 1993b, Microsatellite mapping of the gene causing weaver disease in cattle will allow the study of an associated quantitative trait locus, Proc. Natl. Acad. Sci. USA 90: 1058.PubMedCrossRefGoogle Scholar
  15. Georges, M., Nielsen, D., Mackinnon, M., Mishra A., Okimoto, R., Pasquino, A.T., Sargeant, L.S., Sorensen, A., Steele, M.R., Zhao, X., Womack, J.E., and Hoeschelel, I., 1995, Mapping quantitative trait loci controlling milk production in dairy cattle by exploiting progeny testing, Genetics 139: 907.PubMedGoogle Scholar
  16. Iannuzzi, L, Di Meo, G.P., Gallagher, D.S., Ryan, A.M., Ferrara, L, and Womack, J.E., 1993, Chromosomal localization of omega and trophoblast interferon genes in goat and sheep by fluorescent insitu hybridization, J. Hered. 84: 301.PubMedGoogle Scholar
  17. Lander, E.S., and Botstein, D., 1989, Mapping mendelian factors underlying quantitative traits using RFLP linkage maps, Genetics 121: 185.PubMedGoogle Scholar
  18. Lewin, H.A., Wu, M.-C., Stewart, J.A., and Nolan, T.J., 1988, Association between BolLA and subclinical bovine leukemia virus infection in a herd of Holstein-Friesian cows, Immuno. 27: 338.CrossRefGoogle Scholar
  19. Montgomery, G.W., Crawford, A.M., Penty, J.M., Dodds, K.G., Ede, A.J., Henry, H.M., Pierson, C.A., Lord, EA., Galloway, S.M., Schmack, A.E., Sise, J.A., Swarbrick, P.A., Hanrahan, V., Buchanan, F.C., and Hill, D.F., 1993, The ovine Booroola fecundity gene (FecB) is linked to markers from a region of human chromosome 4q, Nature Genetics 4: 410.PubMedCrossRefGoogle Scholar
  20. Nadeau, J.H., 1989, Maps of linkage and synteny homologies between mouse and man, Trends in Genet 5: 82.CrossRefGoogle Scholar
  21. O’Brien, S.J., 1992, Mammalian genome mapping; lessons and prospects, Curr. Opinion Genetics Develop. 1: 105.CrossRefGoogle Scholar
  22. O’Brien, S.J., Womack, J.E., Lyons, LA., Moore, K.J., Jenkins, N.A., and Copeland, N.G., 1993, Anchored reference loci for comparative genome mapping in mammals, Nature Genetics 3: 103.PubMedCrossRefGoogle Scholar
  23. Otsu, K., Khanna, V.K., Archibald, A.L, and MacLennan, D.H., 1991, Cosegregation of porcine malignant hyperthermia and a probable causal mutation in the skeletal muscle ryanodine receptor gene in backcross families, Genomics 11: 744.PubMedCrossRefGoogle Scholar
  24. Paterson, A.H., Lander, E.S., Hewitt, J.D., Peterson, S., Lincoln, S.E., and Tanksley, S.D., 1989, Resolution of quantitative traits into Mendelian factors by using complete linkage map of restriction fragment length polymorphisms, Nature 335: 721.CrossRefGoogle Scholar
  25. Rettenberger, G., Klett, C., Zechner, U., Kunz, J., Vogel, W., and Hameister, H., 1995, Visualization of the conservation of synteny between humans and pigs by heterologous chromosomal painting, Genomic 26: 372.CrossRefGoogle Scholar
  26. Rohrer, G.A., Alexander, LJ., Keele, J.W., Smith, T.P., and Beattie, C.W., 1994, A microsatellite linkage map of the porcine genome, Genetics, 136: 231.PubMedGoogle Scholar
  27. Rommens, J.M., Iannuzzi, M.C., Kerem., B.-S., Drumm, M.L, Melmer, G., Dean, M., Rozmahel, R., Cole, J.L, Kennedy, D., Hidaka, N., Zsiga, M., Buchwald, M., Riordan, J.R., Tsui, L-C., and Collins, F.S., 1989, Identification of the cystic fibrosis gene: chromosome walking and jumping, Science 245: 1059.Google Scholar
  28. Ryan, A.M., Gallagher, D.S., Jr., Schöber, S., Schwenger, B., and Womack, J.E., 1994, Somatic cell mapping and in situ localization of the bovine uridine monophosphate synthase gene (UMPS), Mammal. Gen orne 5: 46.CrossRefGoogle Scholar
  29. Schwenger, B., Schöber, S. and Detlef, S., 1993, DUMPS cattle carry a point mutation in the uridine monophosphate synthase gene, Genomics 16: 241.PubMedCrossRefGoogle Scholar
  30. Shuster, D.E., Kehrli, Jr., M.E., Ackermann, M.R., and Gilbert, R.O., 1992, Identification and prevalence of a genetic defect that causes leukocyte adhesion deficiency in Holstein cattle, Proc. Natl. Acad. Sci. USA, 89: 9225.PubMedCrossRefGoogle Scholar
  31. Solinas-Toldo, S., Fries, R., Steffen, P., Neibergs, H.L, Barendse, W., Womack, J.E., Hetzel, D.J.S., and Stranzinger, G., 1993, Physically mapped, cosmid-derived microsatellite markers as anchor loci on bovine chromosomes, Mammal. Genome 4: 720.CrossRefGoogle Scholar
  32. Soller, M., and Beckmann, J.S., 1982, Restriction fragment length polymorphisms and genetic improvement, Proc. 2nd World Congress Genetics Applied to Livestock Production 6: 396.Google Scholar
  33. Southern, E, 1975, Detection of specific sequences among DNA fragments separated by gel electrophoresis, J. Mol. Biol. 98: 503.PubMedCrossRefGoogle Scholar
  34. Smith, C., and Simpson, S.P., 1986, The use of genetic polymorphism in livestock improvement, J. Anim. Breed. Genetics 103: 205.CrossRefGoogle Scholar
  35. Threadgill, D.S., Krause, J.P., Krawetz, S.A., and Womack, J.E., 1991, Evidence for the evolutionary origin of human chromosome 21 from comparative gene mapping in the cow and mouse, Proc. Natl. Acad. Sci. USA, 88: 154.PubMedCrossRefGoogle Scholar
  36. Trask, B.J., 1991, Fluorescence in situ hybridization, Trends in Genetics 7:150.Google Scholar
  37. Van Eijk, M.J.T., Russ, I., and Lewin, H.A., 1993, Order of bovine DRB3, DYA, and PRL determined by sperm typing, Mammal. Genome 4: 113.CrossRefGoogle Scholar
  38. Weber, J.L, and May, P.E, 1989, Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction, Amer. J. Human Genetics 44: 388.Google Scholar
  39. Weller, J.L, Kashi, Y., and Soller, M., 1990, Power of daughter and grandaughter designs for determining linkage between marker loci and quantitative trait loci in dairy cattle, J. Dairy Sci. 73: 2525.PubMedCrossRefGoogle Scholar
  40. Womack, J.E., and Moll, Y.D., 1986, A gene map of the cow: Conservation of linkage with mouse and man, J. Hered. 77: 2.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • James E. Womack
    • 1
  1. 1.Department of Veterinary PathobiologyTexas A&M UniversityCollege StationUSA

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