Treatment of Human Circadian Rhythm Sleep Disorders

  • Tatsuro Ohta
  • Toshiji Hayakawa
  • Yuhei Kayukawa
  • Tamotsu Okada


In humans, external factors that are likely to affect on the biological rhythm (time cues) include the following: (1) the time on a clock, (2) light—dark cycle, (3) social interaction, (4) timing of dietary intake, and (5) sleep—wake schedule. Although the light—dark cycle is thought to be the strongest time cue in plants and animals, social interaction is believed to be the most potent time cue in humans (Aschoff, 1965). However, recent studies have revealed that light also exerts a strong influence on the human circadian rhythm (Lewy et al., 1980; Czeisler et al., 1986).


Sleep Disorder Rhythm Disorder Sleep Episode Delay Sleep Phase Syndrome Circadian Rhythm Sleep Disorder 
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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Tatsuro Ohta
    • 1
  • Toshiji Hayakawa
    • 2
  • Yuhei Kayukawa
    • 1
  • Tamotsu Okada
    • 1
  1. 1.Department of PsychiatryNagoya University School of MedicineNagoyaJapan
  2. 2.Department of Clinical LaboratoryNagoya University HospitalNagoyaJapan

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