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Oxaliplatin: Update on a Active and Safe Dach Platinum Complex

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Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2

Abstract

Since the introduction of cisplatin (CDDP) in oncological chemotherapy, numerous attempts have been made to synthetize derivates that would increase the therapeutic index of this cytotoxic class, while expanding its indications. During the past decade, many platinum based therapeutic programs have been aimed at circumventing cisplatin/carboplatin resistance, as primary or acquired treatment failure represents the major limitation of the two platinum complexes currently available in the clinic [1, 2].

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Authors and Affiliations

  1. Service des Maladies Sanguines et Tumorales, Hôpital Paul Brousse, 12-14 Avenue Paul Vaillant Couturier, 94804, Villejuif, France

    P. Soulié, E. Raymond, J. L. Misset & E. Cvitkovic

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  1. P. Soulié
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  2. E. Raymond
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  3. J. L. Misset
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  4. E. Cvitkovic
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Editors and Affiliations

  1. Free University, Amsterdam, The Netherlands

    H. M. Pinedo

  2. Netherlands Cancer Institute, Amsterdam, The Netherlands

    J. H. Schornagel

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© 1996 Springer Science+Business Media New York

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Soulié, P., Raymond, E., Misset, J.L., Cvitkovic, E. (1996). Oxaliplatin: Update on a Active and Safe Dach Platinum Complex. In: Pinedo, H.M., Schornagel, J.H. (eds) Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0218-4_14

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  • DOI: https://doi.org/10.1007/978-1-4899-0218-4_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0220-7

  • Online ISBN: 978-1-4899-0218-4

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