Abstract
A common feature of neurodegenerative diseases such as Parkinson’s disease is the selective, inappropriate death of specific populations of central neurons. In Parkinson’s disease, dopaminergic neurons are lost in the zona compacta of the substantia nigra.1 This selective neuronal death gives rise to a progressive movement disorder whose cause is unknown and for which there is no known cure.
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Trimmer, P.A., Tuttle, J.B., Sheehan, J.P., Bennett, J.P. (1996). Mechanisms of Selective Neuronal Vulnerability to 1-Methyl-4-Phenylpyridinium (MPP+) Toxicity. In: Fiskum, G. (eds) Neurodegenerative Diseases. GWUMC Department of Biochemistry and Molecular Biology Annual Spring Symposia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0209-2_53
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DOI: https://doi.org/10.1007/978-1-4899-0209-2_53
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