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Vitamin E

Neurochemical Aspects and Relevance to Nervous System Disorders

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Metals and Oxidative Damage in Neurological Disorders

Abstract

The history of vitamin E dates back to 1922 when Evans and Bishop (1922) discovered it as a nutritional factor that prevented resorption of the fetus in the laboratory rat. Since then innumerable investigations have been conducted to understand the role of vitamin E in maintaining the structure and function of various tissues. A few years ago this author reviewed selected aspects of the neurochemistry of vitamin E (Vatassery, 1992). The current article is intended to describe the state of the art with respect to the neurobiology of vitamin E, with special emphasis on human neurological diseases. The last section of the chapter summarizes part of the work done in our laboratory. During the last few years many new studies have appeared on this subject. The goal of the current review is not to present a comprehensive review of the field but to highlight some of the new information that has appeared in the literature.

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Authors and Affiliations

  1. Research Service and the Geriatric Research Education and Clinical Center (GRECC), Veterans Affairs Medical Center, Minneapolis, Minnesota, 55417, USA

    G. T. Vatassery

  2. Department of Psychiatry, University of Minnesota, Minneapolis, Minnesota, 55455, USA

    G. T. Vatassery

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  1. G. T. Vatassery
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Editors and Affiliations

  1. Pennsylvania State University, Hershey, Pennsylvania, USA

    James R. Connor

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Vatassery, G.T. (1997). Vitamin E. In: Connor, J.R. (eds) Metals and Oxidative Damage in Neurological Disorders. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0197-2_10

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  • DOI: https://doi.org/10.1007/978-1-4899-0197-2_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0199-6

  • Online ISBN: 978-1-4899-0197-2

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