Metabolic Depression in the Striatum, Thalamus and Cerebral Cortex due to Lesions in the Globus Pallidus

  • Hiroshi K. Inoue
  • Satoru Horikoshi
  • Chihiro Ohye
Part of the Advances in Behavioral Biology book series (ABBI, volume 47)


The functions and roles of the globus pallidus in the human brain are both unclear and difficult to examine. Data are predominantly available only from patients with localized lesions in the globus pallidus. Movement disorders and changes in mental activity have been reported in these patients (Rondolt and Bathien, 1994; Laplane, 1994). It is hypothesized that pallidal lesions influence functioning of the striatum and thalamus via afferent and efferent connections, respectively. Mental changes recognized in patients with bilateral lesions have suggested the concentration of information from the entire cortex in the globus pallidus (Percheron et al., 1984a, Laplane, 1994). Thus, the relationship between pallidal lesions and related areas may be important for understanding the roles of the globus pallidus. Metabolic studies in patients with pallidal lesions may help identify these related areas.


Cerebral Cortex Basal Ganglion Globus Pallidus Striatal Neuron Bilateral Lesion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Hiroshi K. Inoue
    • 1
  • Satoru Horikoshi
    • 1
  • Chihiro Ohye
    • 1
  1. 1.Department of NeurosurgeryGunma University School of MedicineMaebashi, Gunma, 371Japan

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