Overlapping Striatal Distribution of Cortical Inputs from the Primary and Supplementary Motor Areas in the Macaque Monkey
The question of segregated circuitry through the basal ganglia has been a key issue regarding the functional organization of this system. Accumulated evidence has suggested that sensorimotor, association, and limbic cortical areas project in a segregated manner onto three distinct striatal regions, and this segregation is maintained through the basal ganglia to the thalamus (Parent and Hazrati, 1995). Moreover, within the sensorimotor circuit, different motor cortical subdivisions have been proposed to establish the segregated cortico-basal ganglia-thalamo-cortical loops (Alexander and Crutcher, 1990; Strick et al., 1995). That is, individual motor cortical areas project to topographically distinct portions in the striatum, and this segregated arrangement is maintained throughout the loop back to the same cortical areas.
KeywordsBasal Ganglion Caudate Nucleus Supplementary Motor Area Macaque Monkey Dense Label
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