Overlapping Striatal Distribution of Cortical Inputs from the Primary and Supplementary Motor Areas in the Macaque Monkey

  • Masahiko Inase
  • Sharleen T. Sakai
  • Jun Tanji
Part of the Advances in Behavioral Biology book series (ABBI, volume 47)


The question of segregated circuitry through the basal ganglia has been a key issue regarding the functional organization of this system. Accumulated evidence has suggested that sensorimotor, association, and limbic cortical areas project in a segregated manner onto three distinct striatal regions, and this segregation is maintained through the basal ganglia to the thalamus (Parent and Hazrati, 1995). Moreover, within the sensorimotor circuit, different motor cortical subdivisions have been proposed to establish the segregated cortico-basal ganglia-thalamo-cortical loops (Alexander and Crutcher, 1990; Strick et al., 1995). That is, individual motor cortical areas project to topographically distinct portions in the striatum, and this segregated arrangement is maintained throughout the loop back to the same cortical areas.


Basal Ganglion Caudate Nucleus Supplementary Motor Area Macaque Monkey Dense Label 
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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Masahiko Inase
    • 1
  • Sharleen T. Sakai
    • 2
  • Jun Tanji
    • 3
  1. 1.Molecular and Cellular Neuroscience SectionElectrotechnical LaboratoryTsukuba 305Japan
  2. 2.Department of AnatomyMichigan State UniversityEast LansingUSA
  3. 3.Department of PhysiologyTohoku University School of MedicineSendai 980Japan

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