Pathogenesis of HIV-Associated Lymphoma

  • Valerie L. Ng
  • Michael S. McGrath


The diagnosis of HIV-associated lymphoma was first incorporated in 1985 into the Centers for Disease Control’s (CDC) case definition of AIDS (Harnly et al., 1988; Kristal et al., 1988). The incidence of lymphoma in the HIV-1-infected population has been steadily increasing since, and represented 3–4% of AIDS-defining illnesses reported to the CDC in 1991. Except for a surprisingly high incidence of lymphoma observed in one small cohort of HIV-infected individuals (Pluda et al., 1990), there has been no apparent increase in the incidence of lymphoma disproportionate to that for new AIDS diagnoses.


Human Immunodeficiency Virus Primary Central Nervous System Lymphoma Acquire Immunodeficiency Syndrome Heavy Chain Variable Region Advanced Human Immunodeficiency Virus Disease 
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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Valerie L. Ng
    • 1
  • Michael S. McGrath
    • 2
  1. 1.Departments of Laboratory Medicine and MedicineUniversity of California, San Francisco, and San Francisco General HospitalSan FranciscoUSA
  2. 2.Departments of Laboratory Medicine, Medicine, and PathologyUniversity of California, San Francisco, and San Francisco General HospitalSan FranciscoUSA

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