Natural Killer Cells in HIV Infection

  • Benjamin Bonavida
  • Anahid Jewett


Natural killer (NK) cells were originally defined functionally as a lymphocyte subpopulation that spontaneously lysed tumor cells, virally infected cells, and, in some instances, normal cells (Trinchieri, 1989, 1995). It is generally thought that NK cells represent a first line of defense against certain infectious agents and tumor growth. NK cells differ from T or B cells as they do not express known TCR or Ig receptor for antigen. Unlike T cells, NK cells kill target cells in a non-MHC-restricted fashion.


Human Immunodeficiency Virus Natural Killer Natural Killer Cell Human Immunodeficiency Virus Infection Human Immunodeficiency Virus Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Benjamin Bonavida
    • 1
  • Anahid Jewett
    • 1
  1. 1.Department of Microbiology and ImmunologyUniversity of California School of MedicineLos AngelesUSA

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