Natural Killer Cells in HIV Infection
Natural killer (NK) cells were originally defined functionally as a lymphocyte subpopulation that spontaneously lysed tumor cells, virally infected cells, and, in some instances, normal cells (Trinchieri, 1989, 1995). It is generally thought that NK cells represent a first line of defense against certain infectious agents and tumor growth. NK cells differ from T or B cells as they do not express known TCR or Ig receptor for antigen. Unlike T cells, NK cells kill target cells in a non-MHC-restricted fashion.
KeywordsHuman Immunodeficiency Virus Natural Killer Natural Killer Cell Human Immunodeficiency Virus Infection Human Immunodeficiency Virus Disease
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