Taurine 2 pp 385-391 | Cite as

Sodium- and Chloride-Dependent Transport of Taurine at the Blood-Brain Barrier

  • Akira Tsuji
  • Ikumi Tamai
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 403)

Abstract

Sodium- and Cl--dependent taurine transports have been clarified in kidney12 and intestine2. However, there has been only one report, in 1989, for taurine transport at the blood-brain barrier (BBB). This study, using isolated brain capillaries, showed the existence of a Na+-dependent high-affinity uptake system for taurine with a Kt value of about 30 μM at the abluminal membrane4. However, the polarity of taurine transport is difficult to establish with this classical isolated brain capillary technique, because overall uptake may include both luminal and abluminal components.

Keywords

Brain Capillary Endothelial Cell Taurine Transport Sodium Gluconate Taurine Uptake Potassium Gluconate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Akira Tsuji
    • 1
  • Ikumi Tamai
    • 1
  1. 1.Faculty of Pharmaceutical SciencesKanazawa UniversityKanazawaJapan

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