Taurine 2 pp 377-384 | Cite as

High-Affinity Taurine Uptake and Its Regulation by Protein Kinase C in Human Glioma Cells

  • Hirohiko Nakamura
  • Shen Hao Huang
  • Kintomo Takakura
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 403)


In high-resolution 1H NMR spectroscopy, malignant glioma tissues are shown to include higher concentration of taurine than normal brain tissues do. Although it is well known that mouse astrocyte18, rat astrocyte5 and glioma cells12 have a high-affinity uptake system for taurine, little is known about such transport in human glioma cells.


Glioma Cell U373 Cell Phorbol Ester Human Glioma Cell Taurine Level 
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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Hirohiko Nakamura
    • 1
  • Shen Hao Huang
    • 2
  • Kintomo Takakura
    • 3
  1. 1.Department of NeurosurgeryTokyo Metropolitan Komagome HospitalJapan
  2. 2.Sankyo Pharmaceutical Co. Ltd.Japan
  3. 3.Department of NeurosurgeryNeurological Institute of Tokyo Women’s Medical CollegeJapan

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