Taurine 2 pp 371-376 | Cite as

Cellular Studies of the Taurine Transporter

  • Norma Lake
  • John Orlowski
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 403)


It is generally recognized that the amino acid, taurine, is important for the proper functioning of a number of organs, such as the brain, retina, heart, liver and kidney. Individual tissues can maintain high intracellular taurine levels through local biosynthesis, and/or by the transmembrane transport of taurine synthesized either elsewhere in the body (such as in the liver) or obtained from external dietary sources. Taurine exists as a zwitterion at physiological pH and, therefore, diffuses poorly across lipid membrane bilayers6, 7. Hence taurine requires a transporter for efficient entry into cells.


Optic Nerve Taurine Transporter Hybridization Histochemistry Taurine Content Taurine Uptake 
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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Norma Lake
    • 1
    • 2
  • John Orlowski
    • 1
  1. 1.Departments of PhysiologyMcGill UniversityMontrealCanada
  2. 2.Department of OphthalmologyMcGill UniversityMontrealCanada

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