Taurine 2 pp 275-284 | Cite as

Some Actions of Taurine on Ionic Currents of Myocardial Cells and Myometrial Cells

  • N. Sperelakis
  • Y. Katsube
  • M. Kusaka
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 403)


The sulfur amino acid taurine has been reported: (i) to be a positive inotropic (cardiotonic) agent in failing hearts, in both animals and human; (ii) to be depleted in myocardial cells in ischemic heart disease; and (iii) to cause heart failure when deficient in diet of animals (e. g., cats) that cannot synthesize taurine. The taurine content of the heart is elevated in patients and animals with congestive heart failure1. Taurine has been used as a treatment for patients with congestive heart failure (e. g., 3 g per day) by Dr. Azuma et al. In Japan and Korea, soft drinks (e. g., soda pop and fruit drinks) that contain taurine (e. g., 1 g) as an additive are widely available.


Myocardial Cell Pipette Solution Hold Potential Myometrial Cell Taurine Content 
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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • N. Sperelakis
    • 1
  • Y. Katsube
    • 1
  • M. Kusaka
    • 1
  1. 1.Department of Molecular and Cellular PhysiologyUniversity of Cincinnati, College of MedicineCincinnatiUSA

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