Abstract
In the enterohepatic circulation, bile acids have important roles in digesting dietary fat in the intestine. The detergent action of bile acids can be expected to influence biological membranes. In fact, feathery degeneration of hepatocytes and irregular-shaped erythrocytes are seen in chronic cholestatic liver diseases where the concentration of bile acids increases in hepatic tissue and serum.
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References
Dodge, J.T., Mitchell, C., and Hanahan, D.J. 1963, The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes, Arch.Biochem.Biophys. 110:119–130.
Nakashima, T., Nakagawa, Y., Sano, A., Sakamoto, Y., Shima, T., Nakajima, T., Seto, Y., Okuno, T., and Kashima, K. 1990, Regurgitation of bile acids in rat liver under bile drainage: quantitative analysis by taurine or ursodeoxycholate loading test, J.Gastroenterol.Hepatol. 5:121–125.
Nakashima, T., Sano, A., Nakagawa, Y., Okuno, T., Takino, T., and Kuriyama, K. 1983, Effect of taurine on the course of drug-induced chronic liver disease, in: “Sulfur Amino Acids: Biochemical and Clinical Aspects”, Kuriyama, K., Huxtable, R.J. and Iwata, H. eds., Alan R. Liss, Inc., New York, pp. 472
Nakashima, T., Seto, Y., Nakajima, T., Shima, T., Sakamoto, Y., Cho, N., Sano, A., Iwai, M., Kagawa, K., Okanoue, T., and Kashima, K. 1990, Calcium-associated cytoprotective effects of taurine on the calcium and oxygen paradoxes in isolated rat hepatocytes, Liver, 10:167–172.
Nakashima, T., Shima, T., Sakamoto, Y., Nakajima, T., Seto, Y., Sano, A., Iwai, M., Okanoue, T., and Kashima, K. 1993, Effects of bile acids and taurine on the lipid fluidity of hepatic microsomes in normal and bile duct-ligated rats — A spin label study, J.Hepatol. 18:74–79.
Nakashima, T., Takino, T., and Kuriyama, K. 1982, Therapeutic effect of taurine administration on carbon tetrachloride-induced hepatic injury, Jpn.J. Pharmacol. 32:583–590.
Nakashima, T., Takino, T., and Kuriyama, K. 1983, Therapeutic and prophylactic effects of taurine administration on experimental liver injury, in: “Sulfur Amino Acids: Biochemical and Clinical Aspects”, Kuriyama, K., Huxtable, R.J. and Iwata, H. eds., Alan R. Liss, Inc., New York, pp. 449–460.
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© 1996 Springer Science+Business Media New York
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Nakashima, T. et al. (1996). Taurine in the Liver. In: Huxtable, R.J., Azuma, J., Kuriyama, K., Nakagawa, M., Baba, A. (eds) Taurine 2. Advances in Experimental Medicine and Biology, vol 403. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0182-8_10
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DOI: https://doi.org/10.1007/978-1-4899-0182-8_10
Publisher Name: Springer, Boston, MA
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