Abstract
The preimplantation embryo of mammalian species represents the period from fertilisation until the implantation of the embryo into the uterus at the blastocyst stage. In species such as experimental rodents and humans, implantation occurs 4–6 days after fertilisation at which time the embryo has 60–100 cells. During this time the embryo remains free-living within the reproductive tract and there is an exponential increase in cell numbers. Experiments in vitro have shown that growth and development of the embryo during this period is relatively autonomous requiring simple defined medium. There is no apparent absolute requirement for exogenous growth factors. Such autonomy suggests that the stimulus for growth during this period may be endogenous to the embryo.
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© 1996 Springer Science+Business Media New York
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O’Neill, C. (1996). PAF Promotes the Development of the Preimplantation Embryo. In: Nigam, S., Kunkel, G., Prescott, S.M. (eds) Platelet-Activating Factor and Related Lipid Mediators 2. Advances in Experimental Medicine and Biology, vol 416. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0179-8_42
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DOI: https://doi.org/10.1007/978-1-4899-0179-8_42
Publisher Name: Springer, Boston, MA
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