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Purification and Partial Characterization of the PAF Antagonist from the Saliva of the Leech Hirudo Medicinalis

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Book cover Platelet-Activating Factor and Related Lipid Mediators 2

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 416))

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Abstract

We have found in the saliva of the leech Hirudo medicinalis a low-molecular weight fraction which powerfully inhibits platelet aggregation induced by PAF and thrombin, and by no other aggregating agent (1).

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References

  1. M. Orevi, M. Rigbi, E. Hy-Am., Y. Matzner and A. Eldor (1992) A potent inhibitor of platelet activating factor from the saliva of the leech Hirudo medicinalis. Prostaglandins. 43: 483–485.

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Author information

Authors and Affiliations

  1. Department of Biological Chemistry, The Hebrew University of Jerusalem, 91904, Jerusalem, Israel

    Miriam Orevi, Maria-Elisabeth Gödeke & Meir Rigbi

  2. Department of Hematology Tel-Aviv Sourasky Medical Center The Sackler Faculty of Medicine, Tel-Aviv University, Israel

    Amiram Eldor

Authors
  1. Miriam Orevi
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  2. Amiram Eldor
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  3. Maria-Elisabeth Gödeke
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  4. Meir Rigbi
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Editor information

Editors and Affiliations

  1. Free University Berlin, Berlin, Germany

    Santosh Nigam  & Gert Kunkel  & 

  2. University of Utah, Salt Lake City, Utah, USA

    Stephen M. Prescott

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© 1996 Springer Science+Business Media New York

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Orevi, M., Eldor, A., Gödeke, ME., Rigbi, M. (1996). Purification and Partial Characterization of the PAF Antagonist from the Saliva of the Leech Hirudo Medicinalis . In: Nigam, S., Kunkel, G., Prescott, S.M. (eds) Platelet-Activating Factor and Related Lipid Mediators 2. Advances in Experimental Medicine and Biology, vol 416. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0179-8_13

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  • DOI: https://doi.org/10.1007/978-1-4899-0179-8_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0181-1

  • Online ISBN: 978-1-4899-0179-8

  • eBook Packages: Springer Book Archive

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