Abstract
Copper is an essential element by functioning as a cofactor in many redox enzymes such as cytochrome c oxidase, lysyl oxidase, ascorbate oxidase, dopamine β-hydroxylase, tyrosinases and superoxide dismutase. But copper is also very toxic to both eukaryotic and prokaryotic cells: it can initiate the formation of cell damaging radicals which oxidize proteins, DNA and biological membranes. Thus, homeostatic mechanisms have evolved to regulate intracellular copper concentration.
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Duda, P., Strausak, D., Solioz, M. (1996). The Enterococcus hirae Copper ATPases. In: Nève, J., Chappuis, P., Lamand, M. (eds) Therapeutic Uses of Trace Elements. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0167-5_73
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DOI: https://doi.org/10.1007/978-1-4899-0167-5_73
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