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Trace Elements and Other Antioxidants in Alcohol-Related Cirrhosis and Chronic Pancreatitis

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Therapeutic Uses of Trace Elements

Abstract

Excessive alcohol intake is considered to be a major cause for developing cirrhosis and chronic pancreatitis. These two diseases correspond to a degenerative process of tissue parenchyma associated with cell destruction and fibrosis. The cause of both these diseases is probably multifactorial: genetic predisposition, toxic action of alcohol, immune dysregulation, enhancement of fibrosis production and deleterious effect of free radicals. The generation of toxic free radicals from the metabolism of ethanol by hepatic cytochrome P450 II E1 has been implicated in alcoholic liver disease (1).

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Author information

Authors and Affiliations

  1. Department of Hepato-Gastroenterology, Hôpital Erasme, Free University of Brussels, 808 route de Lennik, 1070, Brussels, Belgium

    André Van Gossum

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  1. André Van Gossum
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Editor information

Editors and Affiliations

  1. Free University of Brussels, Brussels, Belgium

    Jean Nève

  2. Lariboisière Hospital, Paris, France

    Philippe Chappuis

  3. National Institute for Agronomic Research, Theix, France

    Michel Lamand

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© 1996 Springer Science+Business Media New York

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Van Gossum, A. (1996). Trace Elements and Other Antioxidants in Alcohol-Related Cirrhosis and Chronic Pancreatitis. In: Nève, J., Chappuis, P., Lamand, M. (eds) Therapeutic Uses of Trace Elements. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0167-5_22

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  • DOI: https://doi.org/10.1007/978-1-4899-0167-5_22

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0169-9

  • Online ISBN: 978-1-4899-0167-5

  • eBook Packages: Springer Book Archive

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