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Determination of the Functions Mediated by each of the Two VEGF Receptors KDR/FLK-1 and FLT-1

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Vascular Endothelium

Part of the book series: NATO ASI Series ((NSSA,volume 294))

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Abstract

Vascular endothelial growth factor (VEGF) binds to two different receptors flt-1 and KDR/flk-1. To determine the functions mediated by each of the VEGF receptors, we compared the effects of VEGF to that of selective flt-1 or flk-1 ligands.

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Authors and Affiliations

  1. Laboratoire de Biologie Moléculaire des Eucaryotes, Centre Nationale de la Recherche Scientifique, Institut de Biologie Cellulaire et Génétique, Toulouse Cédex, France

    Nathalie Ortéga & Jean Plouët

Authors
  1. Nathalie Ortéga
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  2. Jean Plouët
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Editor information

Editors and Affiliations

  1. Vascular Biology Center, Medical College of Georgia, Augusta, Georgia, 30912-2500, USA

    John D. Catravas Ph.D.

  2. Department of Surgery, Boston University School of Medicine, 80 E. Concord Street, NEB 606, Boston, Massachusetts, 02118-2394, USA

    Allan D. Callow M.D., Ph.D.

  3. T Cell Sciences, Inc., 115 4th Avenue, Needham, Massachusetts, 02194-2725, USA

    Una S. Ryan Ph.D.

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© 1998 Springer Science+Business Media New York

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Ortéga, N., Plouët, J. (1998). Determination of the Functions Mediated by each of the Two VEGF Receptors KDR/FLK-1 and FLT-1. In: Catravas, J.D., Callow, A.D., Ryan, U.S. (eds) Vascular Endothelium. NATO ASI Series, vol 294. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0133-0_34

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  • DOI: https://doi.org/10.1007/978-1-4899-0133-0_34

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0135-4

  • Online ISBN: 978-1-4899-0133-0

  • eBook Packages: Springer Book Archive

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