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Targeting of Drugs 6 pp 49–59Cite as

Pegylation of Liposomes in Cell-Specific Targeting: It Does Not Always Make Sense

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Part of the book series: NATO ASI Series ((NSSA,volume 300))

Abstract

Four studies on the use of PEG-ylated liposomes in delivery to liver-associated cells are presented in this paper: (1) hepatocyte-directed delivery; (2) alleviation of Kupffer cell toxicity caused by liposomal doxorubicin; (3) immunospecific delivery to intrahepatic colon tumor cells; (4) scavenger receptor-mediated delivery to hepatic endothelial cells.

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Author information

Authors and Affiliations

  1. Department of Physiological Chemistry, Groningen Institute for Drug Studies, University of Groningen, Medical Sciences, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands

    Gerrit L. Scherphof, Gerben A. Koning, Jan A. A. M. Kamps & Toos Daemen

Authors
  1. Gerrit L. Scherphof
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  2. Gerben A. Koning
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  3. Jan A. A. M. Kamps
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  4. Toos Daemen
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Editor information

Editors and Affiliations

  1. Centre for Drug Delivery Research, The School of Pharmacy, University of London, 29-39 Brunswick Square, London, WC1N 1AX, England, UK

    Gregory Gregoriadis  & Brenda McCormack  & 

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Scherphof, G.L., Koning, G.A., Kamps, J.A.A.M., Daemen, T. (1998). Pegylation of Liposomes in Cell-Specific Targeting: It Does Not Always Make Sense. In: Gregoriadis, G., McCormack, B. (eds) Targeting of Drugs 6. NATO ASI Series, vol 300. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0127-9_6

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  • DOI: https://doi.org/10.1007/978-1-4899-0127-9_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0129-3

  • Online ISBN: 978-1-4899-0127-9

  • eBook Packages: Springer Book Archive

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