Taurine 3 pp 17-23 | Cite as

Hypotaurine Protection on Cell Damage by H2O2 and on Protein Oxidation by Cu++ and H2O2

  • Silvestro Dupré
  • Mara Costa
  • Alessandra Spirito
  • Giuseppina Pitari
  • Paola Rossi
  • Fernanda Amicarelli
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 442)


The antioxidant activity of hypotaurine on cell structure has primarily been studied utilizing artificial liposomes and isolated lipoproteins18. Most studies with whole cells have utilized sperm cells to study the effect of oxidative stress on cellular function in the presence of varying concentrations of hypotaurine1,4,11,14,19. In this paper we will report experiments performed using two in vitro model systems.


Melanoma Cell Neuroblastoma Cell Protein Oxidation Significant Protective Effect Culture Neuroblastoma Cell 
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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Silvestro Dupré
    • 1
  • Mara Costa
    • 1
  • Alessandra Spirito
    • 1
  • Giuseppina Pitari
    • 2
  • Paola Rossi
    • 2
  • Fernanda Amicarelli
    • 2
  1. 1.Dipartimento di Scienze Biochimiche and Centro di Biologia Molecolare del C.N.R.Università di Roma “La Sapienza”RomaItaly
  2. 2.Dipartimento di Biologia di Base ed ApplicataUniversità de L’AquilaL’AquilaItaly

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