Taurine 3 pp 85-89 | Cite as

Effect of Taurine on Biliary Metabolites of Glutathione in Liver Perfused with the Pyrrolizidine Alkaloid, Monocrotaline

  • Chong Chao Yan
  • Ryan J. Huxtable
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 442)


Pyrrolizidines are a group of hepatotoxic plant alkaloids6,9. Certain pyrrolizidines are also toxic to lung, heart, the central nerve system, and other organs. Hepatic bioactivation is required for the expression of toxicity8.


Perfuse Liver Pyrrolizidine Alkaloid Taurine Concentration Taurine Administration Biliary Metabolite 
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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Chong Chao Yan
    • 1
  • Ryan J. Huxtable
    • 1
  1. 1.Department of PharmacologyUniversity of Arizona, College of MedicineTucsonUSA

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