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Depression as a Pivotal Component in Secondary Aging

Opportunities for Research, Treatment, and Prevention

  • Chapter
Book cover Handbook of Aging and Mental Health

Part of the book series: The Springer Series in Adult Development and Aging ((SSAD))

Abstract

There is increasing evidence that depression, together with related affective and behavior symptoms, can play a pivotal role in secondary aging, the process by which medical illnesses accumulate as a correlate of increasing age. In addition to mechanisms by which it can result from psychological mechanisms associated with the stress and losses of function associated with medical illness, depression can result from disease-related changes in the brain and the cerebral environment. Moreover, once depression occurs, it can affect the course of associated medical illness, amplifying distress, disability, morbidity, and, possibly, mortality. Thus, knowledge of depression and of medical—psychiatric comor-bidity in late life can be critical to understanding the downward spiral of deterioration and disability that is frequent in late life.

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  1. Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA

    Ira R. Katz

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  1. Tel Aviv University, Tel Aviv, Israel

    Jacob Lomranz

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Katz, I.R. (1998). Depression as a Pivotal Component in Secondary Aging. In: Lomranz, J. (eds) Handbook of Aging and Mental Health. The Springer Series in Adult Development and Aging. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0098-2_22

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