Single Day Treatment — A Feasible Tool in Revealing Not Dependent on Maternal Toxicity Teratogenic Potential

  • T. Vergieva
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 444)

Abstract

The aim of this study is to explore the applicability of single day treatment for separation of development effects as an intrinsic property from those related to maternal toxicity. The fungicides paclobutrazole and benomyl were administered to pregnant rats on days 6 to 15 and on 7, 9, 11 and 13 day of gestation. After a single treatment higher percentage of fetuses were with external and visceral anomalies.

Keywords

Fetal Weight Cleave Palate Skeletal Anomaly Malformation Rate Maternal Body Weight 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • T. Vergieva
    • 1
  1. 1.Medical Ecology and NutritionNational Center of HygieneSofiaBulgaria

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