Is There a Different Type of MR-Contrast in the Early Phase of Functional Activation?

  • J. Hennig
  • C. Janz
  • O. Speck
  • T. Ernst
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 413)


Conventional functional MR is based on the BOLD-mechanism (1), according to which local hyperperfusion following cortical activation leads to an increase in the oxyhemoglobin concentration of the activated areas, which can be observed by susceptibility sensitive MR imaging techniques such as echo planar imaging (2) or gradient echo imaging with long echo times (3).


Initial Drop Intrinsic Signal Stimulation Cycle Laxation Time Amplitude Effect 
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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • J. Hennig
    • 1
  • C. Janz
    • 1
  • O. Speck
    • 1
  • T. Ernst
    • 1
  1. 1.Abt. RöntgendiagnostikMR-TomographieFreiburgGermany

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