Abstract
Since the pioneering work of Jobsis (1), near-infrared spectrophotometry (NIRS) has been recognized as a unique and powerful tool for non-invasive monitoring of tissue oxygenation. However, even now the quantification of hemoglobin signals and the knowledge of the redox behavior of cytochrome oxidase in vivo, as well as the measurement of cytochrome in the presence of normal blood circulation still pose unresolved issues.
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Tamura, M., Hoshi, Y., Hazeki, O., Okada, F. (1997). Cerebral Oxygenation States as Revealed by Near-Infrared Spectrophotometry. In: Villringer, A., Dirnagl, U. (eds) Optical Imaging of Brain Function and Metabolism 2. Advances in Experimental Medicine and Biology, vol 413. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0056-2_10
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DOI: https://doi.org/10.1007/978-1-4899-0056-2_10
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